Lab Members
Current Lab Members
Professor
- Dr. Tulin received his Ph.D. in Epigenetics from Moscow State University. He was an associate professor at Fox Chase Cancer Center which is a part of of the Temple University System. The long-term goal of Dr. Tulin's research is to explore epigenetics pathways to understand how cells can undergo rapid, local and reversible chromatin reprogramming, thus fine-tuning the induction of local gene activity. His key discovery has been that Poly(ADP-ribose)Polymerase 1 (PARP1) controls chromatin decondensation at large number of loci including hormone-dependent developmental, heat shock responsive, and immunity genes. Understanding how PARP1 acts within normal, undamaged chromatin advances our knowledge of developmental gene regulation and facilitates the development of new anti-cancer drugs for clinical applications and of methods to experimentally re-program gene expression.
Research Specialist
Specialties: Effects of PARP-1 and PARG dysregulation during the onset of prostate, kidney, and
breast cancers.
Research Specialist
Specialties: Poly(ADP-ribosyl)ation pathway in various types of cancer in vitro and in vivo; effect
of overexpression of poly(ADP-ribose) glycohydrolase (PARG) in cancer cells in vitro
and in vivo.
Guillaume Bordet
Postdoctoral Associate
Specialties: Epigenetics in normal development, chromatin regulation, role of Poly(ADP-ribose)
polymerase (PARP) and poly(ADP-ribose) glycohydrolase in transcription regulation,
Drosophila model organisms, protein-chromatin interaction, transcriptomic analysis.
Iaroslava Karpova
Postdoctoral Associate
Specialties: Epigenetic regulation of the early embryonic development, morphogenesis and cell differentiation,
the role of protein poly(ADP-ribosyl)ation in chromatin remodeling and gene activation,
PARG and PARPs functioning in mammals.
Ali Divan
Postdoctoral Associate
Specialties: developing new cancer therapies by using high throughput screening techniques to assess
the molecular and phenotypic effects of small molecules on different types of human
cancers.
Sayem Bhuiyan
Graduate Student
Specialties: Involvement of dual localized proteins in communication between mitochondria and nucleus,
interaction of dual localized CG14850 with nuclear and mitochondrial genome in Drosophila,
Chromatin IP sequencing, protein-protein interaction.
Gbolahan Bamgbose
Graduate Student
Shri Patel
Former Lab Members
Yingbiao Ji
Postdoctoral Associate, 2006-2017
- yingbji@vet.upenn.edu
- 701.777.3000
- 2784 Airport Dr Stop 9051 Grand
Forks, ND 58202-9051
Colin James Thomas
Scientific Technician I, 2011-2013
- Colin.Thomas@jefferson.edu
- 701.777.3000
- 2784 Airport Dr Stop 9051 Grand
Forks, ND 58202-9051
Ernest Boamah
Postdoctoral Fellow (NIH), 2009-2016
Niraj Lodhi
Postdoctoral Associate, 2009-2015
Aaron Dan Pinnola
Scientific Technician I, 2008-2010
Chao Wu
Scientific Technician I, 2016-2017
Kirill Kirsanov
Visiting Scientist, 2010-2011
Elena Kotova
Technical Specialist, 2008-2014
Mikael Garabedian
Scientific Technician I, 2010-2012
Natalia M Naumova
Postdoctoral Associate, 2004-2006
Haily Datz
Student Assistant, 2017-2018
Ammini K Menon
Scientific Technician I, 2004-2005
- Sarah Johnson
Research Specialist
Specialties: Specific genes and pathways regulated by each of PARP-1’s binding domains and how
inhibiting PARP-1 via each of these domains will affect downstream cellular functions.
Student Assistants
- Meera Shah, Germantown academy, 2005-2007
- Jordan Konell, Philadelphia Central High School, 2008-2009
- Nikita Tulin, Cedarbrook High School, 2013-2015
- Michelle Currie, Rowan University, 2016-2017
- Jonathan Harbin, Rowan University, 2016
- Michelle Ampofo, Cedarbrook High School, 2016-2017
- Victor Gromoff, UND, 2017
- Breanna McLain, UND, 2017
- Cody Boyle, UND, 2018
- Brett MacLeod, UND, 2018