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  • 8th ANNUAL EPIGENETICS & EPIGENOMICS SYMPOSIUM

Faculty

Catherine Brissette

 

Catherine Brissette, Ph.D.
Professor

701.777.6412 
catherine.brissette@UND.edu

Brissette Lab

My laboratory is interested in how the Lyme disease spirochete, Borrelia burgdorferi, modulates its own epigenome and that of its host, and how those changes contribute to bacterial survival and human disease.

 

Holly Brown-Borg

 

Holly Brown-Borg, Ph.D.
Chester Fritz Distinguished Professor

701.777.3949
holly.brown.borg@UND.edu

Brown-Borg Lab

My lab is interested in understanding the pathways and mechanisms utilized by hormones that lead to delayed aging and less age-related disease. Reduced signaling of the somatotropic axis results in increased cellular stress resistance, maintenance of a young DNA methylation profile, increased health span and extended life span in mice.

Diane Darland

 

Diane Darland, Ph.D.
Professor

701.777.4597
diane.darland@UND.edu

My lab investigates the neural-vascular interactions in early cortical development, focusing on the epigenetic mechanisms that regulate (1) intrinsic cell fate decisions and (2) microenvironmental influences on cell fate determination.

Archana Dhasarathy

 

Archana Dhasarathy, Ph.D.
Associate Professor

701.777.4285
archana.dhasarathy@UND.edu

Dhasarathy Lab

 

 

The overall goal of our research is to investigate epigenetic mechanisms underlying disease states. The basic questions that interest us are (a) how do epigenetic mechanisms regulate gene expression (b) what is the order of these changes, and (c) can we reverse these processes to better manage disease?

susan

Susan Eliazer, Ph.D.

Assistant Professor

701.777.2624

susan.eliazer@UND.edu

 

 

My lab is interested in studying the epigenetics mechnisms of skeletal muscle stem cells in aging and disease.

Keith Henry

 

Keith Henry, Ph.D.
Associate Professor

701.777.2295
keith.henry@UND.edu

Henry Lab

My lab investigates the epigenetic effects of early exposure to selective serotonin re-uptake inhibitors as a possible mechanism to persistent behavioral changes in adult mice.

Manu

 

Manu Manu, Ph.D.
Associate Professor

701.777.4671
manu.manu@UND.edu

My lab researches gene regulatory networks and gene regulation during hematopoietic cell-fate specification.

Barry Milavetz

 

Barry Milavetz, Ph.D. 
Professor

701.777.4708 barry.milavetz@UND.edu

Milavetz Lab

We are using Simian Virus 40 to address fundamental aspects of epigenetic regulation including the organization of nucleosomes on a genome and the role of histone modifications and variants during the initiation and repression of gene expression.

 

Kumi Nagamoto Combs

Kumi Nagamoto-Combs, Ph.D.
Assistant Professor, Neuroscience Outreach Director Behavioral Research Core Facility

701.777.2259
kumi.combs@UND.edu

Nagamoto-Combs Lab

Our research focuses on elucidating mechanisms of behavioral disorders triggered by inflammatory gut-brain communication. Using a mouse model of milk allergy, we investigate molecular events, including transcriptomic and epigenetic changes, that may lead to brain dysfunction.

 

Sergei Nechaev

 

Sergei Nechaev, Ph.D.
Associate Professor

701.777.2566
sergei.nechaev@UND.edu

Nechaev Lab

The lab seeks to understand the mechanisms of transcription-induced epigenetic reprogramming. Using various in vitro cell culture models, we are developing new concepts and technologies to determine how environmental influences and chemotherapy drugs affect normal cell differentiation and influence progression of cancer.

Benjamin Roche

 

Benjamin Roche, Ph.D.
Assistant Professor 

701.777.6101  benjamin.roche@UND.edu 

ROCHE Lab

Most cells in nature exit the cell cycle and enter a non-dividing state. Our research focuses on deciphering the molecular pathways that allow cells to maintain quiescence, and to avoid both senescence and improper cell cycle re-entry. 

motoki

Motoki Takaku, Ph.D. 
Assistant Professor

701.777.2250
motoki.takaku@UND.edu

Takaku LAB

Our laboratory is interested in understanding the function of chromatin regulators (transcription factors and chromatin remodelers) in cancer. Recent large-scale genome profiling revealed frequent mutations on chromatin regulator genes in various cancers.

 

 

Alexei Tulin

 

Alexei V. Tulin, Ph.D.
Professor

701.777.9422
alexei.tulin@UND.edu

Tulin Lab

Epigenetics in normal development and pathogenesis, chromatin regulation, role of poly(ADP-ribose) metabolism in transcription regulation and oncogenesis, PARP-1 inhibitors in oncology, Drosophila and mammalian model organisms.

 Roxanne Vaughan

 

Roxanne Vaughan, Ph.D.
Professor

701.777.3419
roxanne.vaughan@UND.edu

Vaughan Lab

Structure-function properties of the dopamine transporter—a regulator of dopaminergic neurotransmission and site of action of cocaine and amphetamines.

 John Watt

 

John Watt, Ph.D.
Associate Professor

701.777.6225
john.watt@UND.edu

Watt Lab

The long term goal of the my laboratory is to utilize potentially novel epigenetic mechanisms to promote post-injury neuronal survival and regenerative process outgrowth in vivo and utilize this knowledge to reverse age-induced alterations in the epigenetic landscape to promote neuronal survival and process outgrowth in the mature mammalian CNS.

 

 

 

 

UND Epigenetics/Epigenomics
Columbia Hall Rm 1733B
501 N Columbia Rd Stop 9061
Grand Forks ND 58202-9061
P 701.777.2250
UND.info@UND.edu
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    School of Medicine & Health Sciences

    1301 N Columbia Rd Stop 9037
    Grand Forks, ND 58202-9037

    701.777.2514

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