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Therapeutics

OPPORTUNITY NUMBER

OPPORTUNITY TITLE

AGENCY NAME

POSTED DATE

CLOSE DATE

RFA-AG-24-050 Health Equity and the Cost of Novel Treatments for Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Not Allowed) HHS-NIH11 07/19/2023 10/31/2023
PAR-23-238 Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional) HHS-NIH11 07/19/2023 09/07/2026
PAR-23-239 Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional) HHS-NIH11 07/19/2023 09/07/2026
RFA-AT-24-005 Research Resource for Systematic Reviews of Complementary and Integrative Health (R24 Clinical Trial Not Allowed) HHS-NIH11 07/13/2023 08/31/2023
RFA-TR-23-016 Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed) HHS-NIH11 07/05/2023 06/02/2025
PAR-24-025 Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed) HHS-NIH11 06/30/2023 09/07/2026
PAR-24-024 Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed) HHS-NIH11 06/30/2023 09/07/2026
PAR-23-200 NEI Translational Research Program for Therapeutics (R61/R33 Clinical Trial Not Allowed) HHS-NIH11 06/27/2023 03/16/2025
PAR-23-205 NEI Translational Research Program for Therapeutics (R33 Clinical Trial Not Allowed) HHS-NIH11 06/27/2023 03/16/2025
PAR-24-210 Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional) HHS-NIH11 06/20/2023 05/18/2026
PAR-23-195 Simultaneous and Synergistic Multi-Target Validation for Alzheimers Disease-Related Dementias (R61/R33 Clinical Trial not allowed) HHS-NIH11 06/20/2023 09/15/2023
PAR-23-193 Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed) HHS-NIH11 05/19/2023 04/03/2026
RFA-DA-24-029 Advancing Psychedelics Research for Treating Addiction (R61/R33 Basic Experimental Study with Humans Required) HHS-NIH11 05/16/2023 11/02/2023
RFA-DA-24-024 Advancing Psychedelics Research for Treating Addiction (R61/R33 Clinical Trial Required) HHS-NIH11 05/16/2023 11/02/2023
RFA-NS-24-010 Early-Stage Therapy Development for Alzheimer's Disease-Related Dementias (ADRD) (R61/R33 - Clinical Trial Not Allowed) HHS-NIH11 05/15/2023 09/08/2023
PAR-23-177 Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed) HHS-NIH11 05/11/2023 06/19/2025
PAR-23-191 HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional) HHS-NIH11 05/10/2023 12/08/2025
RFA-NS-23-028 HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) HHS-NIH11 04/27/2023 06/09/2025
RFA-DA-24-039 NIH Blueprint for Neuroscience Research: Tools and Technologies to Explore Nervous System Biomolecular Condensates (R21 Clinical Trial Not Allowed) HHS-NIH11 04/24/2023 11/14/2023
RFA-DA-24-021 Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Basic Experimental Studies with Humans Required) HHS-NIH11 04/18/2023 11/13/2023
RFA-DA-24-020 Mechanistic Studies to Investigate the Interrelationship Between Sleep and/or Circadian Rhythms and Substance Use Disorders (R01 Clinical Trials Not Allowed) HHS-NIH11 04/18/2023 11/13/2023
PAR-23-160 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed) HHS-NIH11 04/13/2023 10/17/2024
PAR-23-159 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed) HHS-NIH11 04/13/2023 10/17/2024
PAR-23-105 Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed) HHS-NIH11 01/13/2023 05/07/2025
PAR-23-091 Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed) HHS-NIH11 01/06/2023 09/07/2025
PAR-23-065 NIAID Resource-Related Research Projects (R24 Clinical Trial Not Allowed) HHS-NIH11 11/23/2022 01/07/2026
PAR-23-041 Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders (R21/R33 Clinical Trial Not Allowed) HHS-NIH11 11/01/2022 07/28/2025
RFA-NS-22-070 HEAL Initiative: Development and Validation of Non-Rodent Mammalian Models of Pain(R01 Clinical Trial Not Allowed) HHS-NIH11 08/09/2022 03/06/2024
RFA-NS-23-003 HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional) HHS-NIH11 08/01/2022 06/09/2025
PAR-22-216 NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional) HHS-NIH11 07/14/2022 07/01/2025
PAR-22-189 Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required) HHS-NIH11 07/12/2022 09/11/2025
PAR-22-170 Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed) HHS-NIH11 07/07/2022 09/07/2025
PAR-22-185 Resources Access for Preclinical Integrated Drug Development (RAPIDD) Program (X01 Clinical Trial Not Allowed) HHS-NIH11 05/27/2022 01/17/2025
RFA-OD-22-007 INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) HHS-NIH11 04/05/2022 07/01/2024
PAR-22-139 Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) (R01 Clinical Trial Not Allowed) HHS-NIH11 03/18/2022 05/07/2025
PAR-22-086 Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed) HHS-NIH11 02/18/2022 05/07/2025
PAR-22-085 Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R01 Clinical Trial Not Allowed) HHS-NIH11 02/18/2022 05/07/2025
PAR-22-111 Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01 Clinical Trial Not Allowed) HHS-NIH11 02/04/2022 01/07/2025
PAR-22-100 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R03 Clinical Trial Not Allowed) HHS-NIH11 02/03/2022 10/17/2024
PAR-22-101 Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed) HHS-NIH11 02/03/2022 10/17/2024
PAR-22-082 Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed) HHS-NIH11 02/03/2022 05/07/2025
RFA-HL-23-010 Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed) HHS-NIH11 01/24/2022 12/20/2024
RFA-HL-23-011 Catalyze: Product Definition for Small Molecules and Biologics - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed) HHS-NIH11 01/24/2022 12/20/2024
RFA-HL-23-012 Catalyze: Product Definition for Small Molecules and Biologics - Preliminary Product/Lead Series Identification (R33 - Clinical Trial Not Allowed) HHS-NIH11 01/24/2022 12/20/2024
RFA-NS-22-034 HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed) HHS-NIH11 01/07/2022 12/06/2024
PAR-22-031 Drug Discovery For Nervous System Disorders (R01 Clinical Trials Not Allowed) HHS-NIH11 11/29/2021 01/07/2025
PAR-22-071 Toward Translation of Nanotechnology Cancer Interventions (TTNCI) (R01 Clinical Trial Not Allowed) HHS-NIH11 11/23/2021 11/17/2024
PAR-21-342 Pre-application: Opportunities for Collaborative Research at the NIH Clinical Center (X02 Clinical Trial Optional) HHS-NIH11 11/19/2021 12/13/2023
PAR-22-032 Drug Discovery For Nervous System Disorders (R21 Clinical Trials Not Allowed) HHS-NIH11 11/17/2021 01/07/2025
PAR-22-028 Ultra-Rare Gene-based Therapy (URGenT) Network Resource Access (X01, Clinical Trial Not Allowed) HHS-NIH11 11/09/2021 09/30/2024
PAR-21-355 Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional) HHS-NIH11 11/09/2021 11/16/2024
PAR-21-354 Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R03 - Clinical Trial Optional) HHS-NIH11 11/09/2021 11/16/2024
PAR-21-353 Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional) HHS-NIH11 11/09/2021 11/05/2024
PAR-21-329 Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional) HHS-NIH11 09/22/2021 11/05/2024
PAR-21-338 Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed) HHS-NIH11 09/22/2021 09/13/2024
PAR-21-264 Computationally-Defined Behaviors in Psychiatry (R21 Clinical Trial Optional) HHS-NIH11 07/07/2021 11/01/2023
RFA-ES-21-006 CCRP Initiative: Chemical Threat Agent-induced Pulmonary and Ocular Pathophysiological Mechanisms (R01 Clinical Trial Not Allowed) HHS-NIH11 06/25/2021 09/20/2023
PAR-21-240 Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required) HHS-NIH11 06/14/2021 03/11/2024
PAR-21-241 NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required) HHS-NIH11 06/14/2021 03/11/2024
RFA-NS-21-029 HEAL Initiative: Planning Studies for Initial Analgesic Development [Small Molecules and Biologics] (R61 Clinical Trial Not Allowed) HHS-NIH11 06/08/2021 10/10/2023
PAR-21-211 Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R34 Clinical Trial Required) HHS-NIH11 04/01/2021 03/16/2024
PAR-21-210 Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required) HHS-NIH11 04/01/2021 03/05/2024
RFA-NS-21-016 HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (R34 Clinical Trial Not Allowed) HHS-NIH11 03/11/2021 10/10/2023
PAR-21-123 Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed) HHS-NIH11 03/11/2021 02/20/2024
PAR-21-124 Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed) HHS-NIH11 03/11/2021 02/20/2024
PAR-21-122 Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed) HHS-NIH11 03/11/2021 02/20/2024
PAR-21-131 Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R34 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-135 Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-129 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (Collaborative R01 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-130 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-137 Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-136 Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-134 Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-132 Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required) HHS-NIH11 03/02/2021 02/15/2024
PAR-21-073 NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional) HHS-NIH11 12/01/2020 06/09/2023
PAR-21-033 National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required) HHS-NIH11 11/12/2020 01/07/2024
PAR-20-264 Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed) HHS-NIH11 08/10/2020 09/07/2023
PAR-20-263 Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed) HHS-NIH11 08/10/2020 09/07/2023
PAR-20-180 Identifying Innovative Mechanisms or Interventions that Target Multimorbidity and Its Consequences (R01 Clinical Trial Optional) NIH 04/30/2020 09/07/2023

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P 701.777.6221
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