Graduate Studies

The Biomedical Sciences Graduate Program provides focused training in inflammation and infectious disease, neuroscience, or molecular and cellular biology.

Degrees Offered

We offer three graduate programs in biomedical sciences. Visit the program pages to learn more about admissions requirements, tuition and fees and how to apply.

Curriculum

The overall goals of the curriculum are to develop core competencies in:

  • Regulatory and Ethical Standards
  • Communication
  • Statistics and Data Analysis
  • Scientific Method

Several core courses provide the foundation for these competencies: BIMD501, BIMD502, BIMD 510, BIMD 516, and BIMD 518.

BIMD501 and BIMD502 are advanced, student-driven courses that provide students the opportunity to acquire biomedical sciences content in the context of discovery and application-based learning and will normally be taken during a student’s first year of graduate school. BIMD 510 (Basic Biomedical Statistics) and BIMD 516 (Responsible Conduct in Research) are also taken in the first year. BIMD518 (Grant Writing) will normally be taken during a student’s second year and will provide advanced education in scientific writing, particularly in the arena of grant applications.

Courses Offered

Year One

Fall Semester

  • BIMD501 – Scientific Discovery I – 6 credits
  • BIMD516 – Responsible Conduct in Research – 2 credits
  • Journal Club(s) – required attendance in at least one, no credit or grade
  • Seminar(s) – required attendance, no credit or grade
  • Laboratory Rotations – required, no credit or grade
  • Biosafety/Radiation Safety/HIPAA – required, no credit or grade

Spring Semester

  • BIMD502 – Scientific Discovery II – 6 credits
  • BIMD510 – Basic Biomedical Statistics – 2 credits
  • Journal Club(s) – required attendance in at least one, no credit or grade
  • Seminar(s) – required attendance, no credit or grade
  • Laboratory Rotations – required, no credit or grade
  • Select Advisor (following last rotation)
  • Form student Faculty Advisory Committee
  • Submit Program of Study

Year Two

Fall/Spring Semesters

  • Journal Club(s) – required attendance in at least one, no credit or grade
  • Seminar(s) – required attendance, no credit or grade
  • Research seminar - required
  • Advisory Committee meeting - required
  • Research – credit as necessary
  • BIMD518 - Grant writing – 2 credits
  • Electives – 6 credit minimum over entire graduate career

Summer

  • Comprehensive Examination
  • Advancement to candidacy

Year Three and Beyond

  • Journal Club(s) – required attendance in at least one, no credit or grade
  • Seminar(s) – required attendance, no credit or grade
  • Research seminar – required yearly
  • Advisory Committee meeting – required yearly
  • Research – credit as necessary
  • Electives – as needed
  • Dissertation – 6 credits

BIMD 501. Scientific Discovery I. 6 Credits. Fall semester.

A problem based course in which students will address a set of biomedical research scenarios that have been designed so that students will acquire skills in critical thinking, finding, interpreting, and analyzing scientific literature, developing hypothesis-driven questions, proposing and designing experiments, and communicating scientific outcomes orally and in written format.

BIMD 502. Scientific Discovery II. 6 Credits. Spring semester.

A problem based course in which students will address a set of biomedical research scenarios that have been designed so that students will advance their skills in critical thinking, finding, interpreting, and analyzing scientific literature, developing hypothesis-driven questions, proposing and designing experiments, and communicating scientific outcomes orally and in written format. This course is a continuation and advancement of BIMD501. Prerequisites: BIMD501

BIMD 510. Basic Biomedical Statistics. 2 Credits. Spring semester.

A series of lectures, demonstrations and exercises to provide students with the basic rationales for the use of statistics in the assessment of biomedical data and a selected set of the most common and useful statistical tests.

BIMD 513. Seminars in Biomedical Science. 1 credit.

A series of presentations on original research conducted by UND faculty members as well as extramural leaders in academic and industrial research in the biomedical sciences. Students will participate through assigned reading and writing exercises related to the presentations.

BIMD 516. Responsible Conduct of Research. 1 credit.

A series of lectures and discussion sessions covering topics related to responsible conduct in research. Students will examine a variety of issues including introduction to ethical decision making, the experience of conflict, laboratory practices, data management, reporting of research, conflict of interest, and compliance. Examples and case studies will be drawn primarily from the biomedical sciences.

ANAT 501. Biomedical Information Retrieval. 1 credit. S/U grading only.

Offered every session either in a group setting or on an individual basis. This course integrates electron information retrieval techniques with biomedical research education to develop the student's ability to augment traditional learning and research. Electronic techniques covered include database searching and Internet resources.

ANAT 505. Seminar in Anatomy and Cell Biology. 1 credit.

This course provides students an opportunity to organize and orally present scientific information to an audience in a forum conducive to the development of their skills in effective communication. Seminars delivered by students, UND faculty, and other invited speakers present current advancements in biomedical research that promote student learning of principles of biomedical sciences.

ANAT 513. Gross Anatomy. 6 credits.

Gross Anatomy will be an intensive one semester course that will use a regional approach to enhance the understanding of the structural and functional relationships as well as organization of the adult human body. Lectures will be reinforced with the complete cadaver dissection and multiple clinical imaging modalities to strengthen problem solving and critical thinking skills. Prerequisites: Permission of course director and ANAT 204L or equivalent.

ANAT 517. Principles of Histology. 3 credits.

Principles of Histology is a laboratory and discussion based course that involves a strong self-study component through the use of virtual slides as well as lecture and laboratory orientation videos. By the end of the course the student will have demonstrated a significant knowledge base of tissue microanatomy sufficient for understanding and applying the principles to a wide range of research projects. The student will also have sufficient knowledge of histology to be capable of teaching this material to medical, professional, graduate, and undergraduate students. Prerequisites: None.

ANAT 521. Principles of Developmental Biology. 3 credits.

This is a student driven course designed to provide the student with a firm understanding of the concepts in developmental biology. Students will be using a wide range of materials from textbooks to the internet to gain a graduate level understanding including how to apply this knowledge to research applications. Student presentations will address advanced principles of developmental mechanisms and underlying human embryology. Prerequisites: None.

ANAT 590. Readings in Anatomy and Cell Biology. 1 to 3 credits.

Students may elect to do a "readings" project with any of the members of the departmental faculty, in areas related to the faculty member's research field.

ANAT 591. Special Topics in Anatomy and Cell Biology. 1 to 3 credits. Prerequisite: Permission of the instructor.

A series of lectures, discussions and/or laboratory experiences developed around a specific topic in the anatomical or cell biological sciences.

ANAT 593. Research in Anatomy and Cell Biology. Credits arranged.

Research is offered in the specialty fields of the faculty of the department, and involves a variety of problems and research tools in morphology and cell biology.

 

BMB 514. Current Literature. 1 credit. Prerequisite: BIMD 500 or consent of instructor. S/U grading only.

Students of the department rotate in leading informal reviews, analyses, and the discussions of research papers selected from current journals in the areas of biochemistry and molecular biology.

BMB 521. Seminar. 1 credit. Prerequisite: BIMD 500 or consent of instructor, S/U grading only.

Students present topics in biochemistry and molecular biology based on reviews of the current literature. Each presentation is followed by a discussion of the topic by the faculty and students of the department.

BMB 533. Advanced Topics. 1 credit. Prerequisites: BIMD 500; alternatively, Biochemistry 301 or equivalent and permission of instructor.

The purpose of this course is to provide an in-depth exploration of selected areas of protein structure and function, metabolism, regulation of cell functions, proteomics, recombinant DNA technology, eukaryotic nucleic acid metabolism, and gene expression with the intent of complementing and extending the knowledge base gained in BIMD 500. Extensive independent learning is expected.

BMB 540. Special Topics. 1 to 3 credits. Prerequisite: BIMD 500 or consent of instructor.

Discussion of a topic in biochemistry and/or molecular biology of current interest to faculty and students.

BMB 590. Research. 1 to 12 credits.

The assignments deal with pertinent research problems in various aspects of biochemistry and molecular biology.

BMB 594. Special Problems in Biochemistry and Molecular Biology. 1 to 6 credits. Prerequisite: Consent of instructor.

The student in consultation with a faculty member of the department undertakes a laboratory research project.

BMB 595. Readings in Biochemistry and Molecular Biology. 1 to 3 credits. Prerequisite: BIMD 500 or consent of instructor.

Selected readings and library research in an area of mutual interest to the student and a faculty member of the department. Conferences and/or written reports are required.

BIMD 530. Components of the Immune System. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

Have you ever wondered why you don’t get sick every time you breathe air, which can carry as many as 2000 different kinds of microbes on any given day? Or what keeps your defense system from attacking your own cells but can get rid of most invaders without you even noticing? This is the amazing task of your fascinating immune system! This course will provide an overview of cellular and molecular components of mammalian immune system and their function. The students will learn how these components are derived and how they interact and communicate with each other to coordinate a response to pathological insults in order to protect the human body.

BIMD 531. Components of Microbial Pathogenesis. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

The objective of the course is to provide students with a background in the mechanisms of microbial pathogenesis. Students will learn basic principles of host-parasite interactions. Paradigms of host-parasite interactions will be illustrated by studying, at the molecular and cellular levels, specific infectious diseases and the agents that cause them.

BIMD 532. Microbial Gene Regulation. 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

This course will provide an understanding of genetic regulation in bacteria. Classic pathways will be examined as paradigms of regulatory circuits. These examples will be expanded to learn how bacteria exploit host cells as well as the use of bacterial regulatory circuits in modern molecular biology.

BIMD 533. Microbial Membranes and Transport. 1 credits. Prerequisites: BIMD 502 or Consent of Instructor.

This course will explore bacterial membranes with particular emphasis on generation of energy and transport of molecules across the membranes

BIMD 534. Microbial Structure/Function. 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

Microbial cells have unique structures that relate their functions. Students completing this course will have an understanding of how prokaryotic and eukaryotic organisms differ and how different structures can be used to obtain similar functions. They will understand how microbial structures influence interactions between microbes and between microbes and eukaryotic organisms.

BIMD 535. Bacterial Host-Pathogen Interactions. 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

The objective of the course is to provide students with a background in the fundamental aspects that occur at the bacterial-host interface. Students will learn the interplay between bacterial virulence factors, strategies used to evade host defenses, and host responses to infection.

BIMD 536. Molecular Biology and Pathogenesis of Viruses. 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

This course will cover the structure, replication, and pathogenesis of human RNA and DNA viruses, the host immune response to viral infection and the strategies employed by viruses to escape immune detection and elimination.

BIMD 537. Host-Pathogen Interactions involving Eukaryotic Microbes (Parasites/Fungi). 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

Eukaryotic microbe infections have a devastating impact on global health and economic development as they infect over one third of the world’s population and cause acute and chronic pathologies. Furthermore, macroscopic parasites (helminths/worms) are master regulators of host inflammatory response and hence reduce the immune response to coinfections and negatively affect the success of vaccination programs against many other pathogens. In contrast, it has been proposed that the rise in autoimmune diseases in the developed world could be a direct result of the successful complete elimination of parasitic helminths in these communities. Thus, the purpose of this course is to provide a basic knowledge of the clinically important eukaryotic microbe pathogens and the immune response associated with their infections. A series of lectures will cover course components; a) basic introduction to protozoa, helminth, and fungi, and b) basic knowledge of the immune response and its involvement in parasitic/ fungal infections. An effort has been made to increase clinical relevance and problem-solving skills through a team-learning exercise involving quiz and paper presentations.

BIMD 538. Immunological Disorders. 1 credit. Prerequisites: BIMD 502 or Consent of Instructor.

This course will include discussion of cellular and molecular immunopathologies leading to autoimmune diseases, and primary and secondary immunodeficiencies; and the role of the immune system in tumorigenesis and transplantation, as well as various methods of modification of the immune response.

BIMD 539. Readings in Microbiology and Immunology. 1 to 4 credits repeatable to a maximum of 4 credits. Prerequisite: Consent of instructor.

A supervised readings course of topics of mutual interest to the student and a faculty member.

MBIO 507. Seminar in Microbiology. 1 credit. S/U grading only.

MBIO 511. Microbiology & Immunology Literature 1 credit. S/U grading only. Prerequisite: Microbiology 302 or equivalent.

A series of reports of current scientific literature in Microbiology and Immunology.

MBIO 513. Research Tools. 2 credits.

Orientation to research and laboratory safety. The theory and application of modern laboratory techniques of tissue culture, cell fractionation, enzyme assay, immunization procedures, bacterial growth curves, photomicrography, strain construction, genetic engineering, gel electrophoresis, enzyme immunoassay, and western blot techniques are presented. S/U grading only.

MBIO 515. Advanced Topics. 2 credits. Prerequisite: Previous basic course in the area to be covered.

A series of topics in microbiology and immunology presented on an episodic basis. The topics may vary, but are expected to include: (A) Immunology, (B) Infectious Diseases, and (C) Molecular Biology.

MBIO 517. Advanced Immunology Laboratory. 2 credits. Prerequisite: Microbiology 509 or equivalent.

Laboratory experience will include procedures for analysis of antigens, antibodies and cell mediated immune responses.

MBIO 590. Research in Microbiology. 2 to 6 credits. Hours arranged.

Advanced problems in microbiology and related fields.

MBIO 591. Special Problems in Microbiology. 1 to 6 credits.

Short term research projects performed under the supervision of a department faculty member. Intended to provide interested capable students with a challenge and an opportunity to conduct scientific research in microbiology. Arranged by consultation with participating faculty members.

PPT 500. Principles of Physiology and Pharmacology. 6 credits. Prerequisites: BIMD 500 or consent of instructor.

Graduate level survey course covering basic principles of human physiology and pharmacology. Material covered will include the physiology (how the body works) and the pharmacology (how drugs affect physiological functions) of the major organ systems. Covered also will be basic pharmacological principles including pharmacodynamics, pharmacokinetics and therapeutics. Teaching modalities used are designed to actively engage students in critical thinking and knowledge application.

PPT 503. Advanced Pharmacology or Physiology. 3 credits. Prerequisite: PPT 500 or consent of instructor.

PPT 505. Research Techniques. 1-3 credits. Prerequisite: consent of instructor.

PPT 511. Biochemical and Molecular Mechanisms of Pharmacology. 3 credits. Prerequisites: BIMD 500, PPT 500 or consent of instructor.

Fundamental concepts of pharmacology with emphasis on biochemical and molecular mechanisms.

PPT 512. Special Topics in Pharmacology, Physiology and Therapeutics. 2 credits. Prerequisite: Consent of instructor.

An in-depth coverage of a particular topic chosen by the instructor.

PPT 521. Seminar in Pharmacology, Physiology and Therapeutics. 1 credit.

PPT 525. Advanced Renal Physiology. 3 credits. Prerequisites: PPT 500 or consent of instructor.

PPT 526. Advanced Respiratory Physiology. 3 credits. Prerequisites: PPT 500 or consent of instructor.

PPT 528. Advanced Endocrinology. 3 credits. Prerequisites: PPT 500 or consent of instructor.

PPT 529. Advanced Cardiovascular Physiology. 3 credits. Prerequisites: PPT 500 or consent of instructor.

PPT 530. Advanced Neurochemistry. 3 credits. Prerequisites: PPT 500 or consent of instructor.

This course is designed to introduce graduate students to the discipline of neurochemistry. This course builds on concepts introduced in PPT 500, with an emphasis on brain biochemical processes occurring in health and disease.

PPT 590. Readings in Pharmacology, Physiology and Therapeutics. 1 to 4 credits repeatable to a maximum of 4 credits. Prerequisite: Consent of instructor.

A supervised readings course on topics of mutual interest to the student and a faculty member. Consent of instructor required.

PPT 591. Research in Pharmacology, Physiology and Therapeutics. Credits arranged.

PPT 996. Continuing Enrollment. Consent of instructor required.

PPT 998. Thesis. Credits arranged.

Preparation and defense of a thesis based on original research. Consent of instructor required.

PPT 999. Dissertation. Credits arranged.

Preparation and defense of a dissertation based on original research. Consent of instructor required.

 

BIMD 520. Principles of Neuroanatomy. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

In this course students will learn the fundamental principles of neuroscience, particularly gross and cellular anatomy, development and systems physiology of the nervous system. Behavioral, cognitive and clinical manifestations of abnormal neural functions will also be addressed.

BIMD 521. Neurophysiology. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

This course is designed to introduce students to the electrical properties of neuronal membranes. The course is organized to first provide a brief review of the basic properties of semi-permeable membranes. The electrical and biochemistry principles that apply to neuronal membranes are discussed.

BIMD 522. Principles of Neuropharmacology. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

This course is designed to introduce students to the latest developments in molecular neuropharmacology. The course directive is to provide an up-to-date foundation for clinical neuroscience by emphasizing a comprehensive molecular and cellular approach to the effects of drugs on the nervous system.

BIMD 523. Neurochemical Basis of the Nervous System. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

This course is designed to introduce students to fundamental concepts of brain metabolism and neurochemical signaling. It emphasizes recent advances in understanding brain biochemical processes and molecular mechanisms occurring in health and disease.

BIMD 524. Neurodegenerative Diseases and Pathophysiology. 2 credits. Prerequisites: BIMD 502 or Consent of Instructor.

This course exposes students to diverse neurodegenerative diseases and nervous system pathophysiology. The emphasis is on mechanistic understanding of the most recent advances in the field.

BIMD 525. Readings in Neuroscience. 1 to 4 credits repeatable to a maximum of 4 credits. Prerequisite: BIMD 502 or Consent of Instructor.

A supervised readings course on topics of mutual interest to the student and a faculty member.

Current Student Resources

Biomedical Student Handbook

SGS Guide to Graduation

UND Biomedical Graduate Student Association