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Instruments

Synapt G2S HD Q-TOF Mass Spectrometer with Ion Mobility Technology with UPLC Waters Acquity and nano-UPLC Waters Acquity systems (Waters)

  • High-resolution (40,000) accurate mass (2 ppm) instrument with ESI, APCI, APPI, Solid Probe ion sources, nano-ESI, and ion mobility cell
  • Allows for M.S. and MSe analysis, exact mass, elemental composition, and structure determination of unknown compounds
  • Metabolomics profiling and experimental group metabolome comparison
  • Proteomics analysis

Xevo TQ-S Mass Spectrometer (Waters) coupled to Waters Acquity UPLC-I class system

  • Waters High-sensitivity, low-resolution instrument with ESI and APCI ion sources
  • Allows for a targeted quantification of known compounds using LC-MS/MS approach
  • Available for self operation after training

Polaris Q Trap Mass Spectrometer coupled to TRACE GC Ultra (Thermo Finnigan)

  • Low-Resolution, EI and CI, GC-MS and GC-MS/MSn
  • Allows for quantification of volatile compounds, often requires derivatization
  • Available for self-operation after training

Q Exactive Orbitrap coupled to Waters NanoAcquity UPLC

  • High-resolution (250,000) accurate mass (0.5 ppm) instrument with ESI and nano-ESI ion sources
  • Allows for metabolomics and proteomics profiling, and protein and metabolite ID

API 3000 coupled to Agilent HPLC coupled to Agilent HPLC

  • An old but very robust system
  • High sensitivity, low-resolution instrument with ESI, APCI, Photon Ionization ion sources
  • Allows for a targeted quantification of known compounds using LC-MS/MS approach

Mikhail Golovko, Ph.D.
Mass Spectrometry Director
Assistant Professor
Pharmacology, Physiology & Therapeutics
701.777.2305
mikhail.golovko@UND.edu

Svetlana Golovko
Research Specialist
701.777.3574
svetlana.golovko@UND.edu

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School of Medicine & Health Sciences

1301 N Columbia Rd Stop 9037
Grand Forks, ND 58202-9037

701.777.2514

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