Publications

2024

Wang Z, Gao P, Guo, K, Schirrick G, Singh Gill, J, Weis J, Lund Da Costa A, Rahman, M Mehta H, Fleecs J, Jain S, Debnath T, Jur J, Khan N, Sticca R, Brown-Borg H, Jurivich DA, Mathur R. 2024. Age-related dysregulation of intestinal epithelium fucosylation is linked to an increased risk of colon cancer. JCI Insight 9(5):e167676. doi: 10.1172/jci.insight.167676.

2023

Trivedi R, Knopf B, Rakoczy S, Manocha GD, Brown-Borg H, Jurivich DA. 2023. Disrupted HSF1 regulation in normal and exceptional brain aging. Biogerontology Sept 14. doi: 10.1007/s10522-023-10063-w.
Perazza LR, Gower AC, Brown-Borg HM, Divieti P, Thompson LV. 2023. Protectin DX as a therapeutic strategy against frailty in mice. Geroscience doi: 10.10007/s11357-023-00789-3. PMID: 37059838
Han J, Wang J, Shi H, Li Q, Zhang S, Wu H, Li W, Zhuang C, Gan L, Chen Y, Feng W, Brown-Borg HM, Zhao 2023. Ultrasmall polydopamine Nanomedicine-enabled antioxidation against senescence. Materials Today Bio 19:100544. doi: 10.1016/j.mtbio.2023.10054. PMID: 3674780
Villeda S, Brown-Borg H, Anderson R. 2023. Neurobiology of aging: New insights from across the research spectrum. J Gerontology Biological Sciences Jun 1;78(6):869-871. doi: 10.1093/gerona/glad110.

2022

Noureddine S, Saccon T, Rudeski-Rohr;T, Gesing A, Mason JB, Schneider A, Dhabhi J, Puig KL, Rakoczy S, Brown-Borg HM, Masternak MM. 2022. GH-deficiency confers protective advantages against Alzheimer’s disease through rescued miRNA expression profile in APP/PS1 mice. Geroscience 44(6):2885-2893. doi: 10.1007/s11357-022-00633-0. PubMed PMID: 35900661.
Perazza L, Brown-Borg HM, Thompson LV. 2022. Physiological systems promoting frailty. Comprehensive Physiology. 12(3):3575-3620. Doi: 10.1002/cphys.c210034.
Brown-Borg HM. 2022. Growth hormone, not IGF-1 is the key longevity regulator in mammals. J Gerontol A Bio Sci Med Sci 77(9):1719-1723. doi: 10.1093/gerona/glac092.
Nacarelli T, Azar A, Potnis M, Johannes G, Mell J, Bene M, Johnson FB, Brown-Borg H, Nogouchi E, Sell C. 2022. The methyltransferase enzymes, KMT2D, SETD1B, and ASH1L, are key mediators of both metabolic and epigenetic changes during cellular senescence. Molecular Biology of the Cell 33:5:ar36.doi: 10.1091/mbc.E20-08-0523.
Kai G, Wang Z, Debnath T, Mehta H, Abrham E, Even Z, Rahman M, Lund Da Costa A, Jain S, Wang X, Hur J, Gopal M, Ting A, Brown-Borg HM, Jurivich DA, Khan N, Mathur R. 2022. Mitochondrial transcription factor A regulates Foxp3+ T cell mediated maintenance of CD4+ T cell landscapes and immunological aging. bioRxiv 2022.03.08.483517; doi: https://doi.org/10.1101/2022.03.08.483517

2021

Trivedi R, Knopf B, Tripathi JK, Rakoczy S, Manocha GD, Brown-Borg HM, Jurivich D. 2021. Augmentation of the heat shock axis during exceptional longevity in Ames dwarf mice. Geroscience 43(4):1921-1934.doi: 10.1007/s11357-021-00362-w.
Zhu R, Yan, T, Feng Y, Liu Y, Cao H, Peng G, Yang Y, Xu Z, Liu J, Hou W, Wang X, Li Z, Deng L, Wang S, Li J, Han Q, Li H, Shan G, Cao Y, An X, Yan J, Zhang Z, Li H, Qu X, Zhu J, Zhou S, Wang J,Zhang F, Gao J, Jin R, Xu D, Ma Y, Huang T, Peng S, Zheng Z, Stambler I, Gilson E, Lim LW, Moskalev A, Cano A, Chakrabarti S, Ulfhake B, Su H, Xu H, Xu S, Wei F, Brown-Borg HM, Min K-J, Ellison-Hughes G, Caruso C, Jin K, Zhao RC. 2021. Mesenchymal stem cell treatment improves outcomes in COVID-19 patients via multiple immunomodulatory mechanisms. Cell Research-Nature 26:1-19. doi: 10.1038/s41422-021-00573-y.
Pabis K, Chiari Y, Sala C, Straka E, Giacconi R, Provinciali M, Brown-Borg H, Nowikovsky K, Valencak T, Gundacker C, Garagnani P, Malavolta M. 2021. Elevated metallothionein in long-lived species mediates the influence of cadmium accumulation on aging. Geroscience 43(4):1975-1993. doi: 10.1007/s11357-021-00393-3.
Tomkinson GR, Kidokoro T, Dufner T, Noi S, Fitzgerald JS, Brown-Borg HM. 2021. Temporal trends in the 6-minute walking distance of older Japanese adults between 1998 and 2017. Journal of Sport and Health Science 10(4):462-469. doi: 10.1016/j.jshs.2020.06.007.

2020

Buffenstein R, Lewis KN, Gibney PA, Grimes K, Narayan V, Smith M, Lin T, Brown-Borg HM. 2020. Probing paedomorphy and prolonged lifespan in the naked mole-rats and dwarf mice. Physiology 35(2): 96-111. doi.org/10.1152/physiol.00032.2019
Jurivich D, Manocha G, Trivedi R, Lizakowski M, Rakoczy S, Brown-Borg H. 2020. Multi-factorial attenuation of the murine heat shock response with age. J Gerontol A Biol Sci 75(10):1846-1852. doi:10.1093/gerona/glz204.
Brown-Borg HM. 2020. ‘A glance back’ at the Journals of Gerontology: We’ve come a long way, baby! J Gerontol A Biol Sci Med Sci 75(2):205-206. doi: 10.1093/gerona/glz170.
Thelen M, Brown-Borg HM. 2020. Does diet have a role in the treatment of Alzheimer’s disease? Frontiers in Aging Neuroscience. 12:617071. doi: 10.3389/fnagi.2020.627071.

2019

Royce GH, Brown-Borg HM, Deepa SS. 2019. The potential role of necroptosis in inflammaging and aging. Geroscience 41(6):795-811. Doi:10.1007/s11357-019-00131-w.

2018

Brown-Borg HM, Rakoczy S, Wonderlich JA, Borg KE, Rojanathammanee L. 2018. Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation. Annals of the New York Academy Sciences 1418(1):118-136. doi: 10.1111/nyas.13687.
Brown-Borg HM, Borg KE. 2020. A summary of the Proceedings of the Fourteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 15-20, 2018. Geroscience 42(5):1195-1198. doi: 10.1007/s11357-020-00234-9.

2017

Cole JJ, Robertson NA, Rather MI, McBryan T, Brock C, Clark W, Miller RA, Brown-Borg H*, and Adams PD* (2017) Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology 18(1):58. *Corresponding authors. Genome Biology
Wang T, Tsui B, Kreisberg JF, Robertson NA, Gross AM, Carter H, Brown-Borg H, Adams PD, and Ideker T (2017) Epigenetic aging signatures in mice is slowed by dwarfism, caloric restriction and Rapamycin treatment. Genome Biology. 18(1):57. Genome Biology
Brown-Borg HM and Borg KE (2017) A summary of the Proceedings of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 17-22, 2016. Experimental Gerontology (in press). PubMed
Brown-Borg HM, Anderson RM. 2017. Metabolic adventures in aging research. Molecular and Cellular Endocrinology 455 (1-3)
Brown-Borg HM. Disentangling high fat, low carb and healthy aging. 2017. Cell Metabolism 26(3):458-459.

2016

Brown-Borg HM and Buffenstein R (2016) Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan? Ageing Research Reviews pii: S1568-1637(16)30204-5. doi: 10.1016/j.arr.2016.08.007. PubMed
Puig KL, Kulas JA, Franklin W, Rakoczy SG, Taglialatela G, Brown-Borg HM, and Combs CK (2016) The Ames dwarf mutation attenuates Alzheimer’s disease phenotype of APP/PS1 mice. Neurobiology of Aging 40:22-40. doi: 10.1016/j.neurobiolaging.2015.12.021. PubMed

2015

Brown-Borg HM (2015) Reduced GH signaling and methionine restriction: Interventions that improve metabolic health and lifespan. Annals of the New York Academy of Sciences. 1363(1):40-49. PubMed
Brown-Borg HM (2015) The somatotropic axis and longevity in mice. Am J Physiology Endo Metab. 309(6):E503-510. doi:10.1152/ajpendo.00262.2015. PubMed
Brown-Borg HM and Borg KE (2015) A summary of the proceedings of the Twelfth International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 27-August 1, 2014. Experimental Gerontology doi:10.1016/j.exger.2015.01.004. PubMed
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y ,Vijg J, Vinciguerra M, and Fontana L (2015) Interventions to slow aging in humans: Are we ready? Aging Cell 14(4):497-510. doi: 10.1111/acel.12338. PubMed

2014

Brown-Borg HM, Rakoczy S, Wonderlich JA, Armstrong V, and Rojanathammanee L (2014) Altered dietary methionine differentially impacts glutathione and methionine metabolism in long living growth hormone deficient Ames dwarf and wild type mice. Longevity and Healthspan 3:10. doi:10.1186/2046-2395-3-10. PubMed
Brown-Borg HM, Rakoczy S, Wonderlich JA, Rojanathammanee L, Kopchick JJ, Armstrong V, and Raasakka D (2014) Growth hormone signaling is necessary for lifespan extension by dietary methionine. Aging Cell 13(6):1019-1027. doi: 10.1111/acel.12269. Anatomical Society
Rojanathammanee L, Rakoczy S, Kopchick JJ, and Brown-Borg HM (2014) Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice. AGE 36(4):9687-9693. doi: 10.1007/s11357-014-9687-3. PubMed
Ables GP, Brown-Borg HM, Buffenstein R, Church CD, Elshorbagy AK, Gladyshev VD, Huang T, Miller RA, Mitchell JR, Richie JP, Rogina B, Stipanuk MH, Orentreich DS, and Orentreich N, (2014) The first international mini-symposium on methionine-restriction and lifespan. Frontiers in Genetics: Genetics of Aging 5:122. 09 May/doi: 10.3389/fgene.2014.00122. PubMed
Derenne A, Brown-Borg HM, Martner S, Wolff W, and Frerking M (2014) Spatial delayed nonmatching-to-sample performances in long-living Ames dwarf mice. Physiology and Behavior 123:100-104. PMID 24140989. PubMed
Rojanathammanee L, Rakoczy S, and Brown-Borg HM (2014) Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 69(10):1199-1211. doi: 10.1093/gerona/glt178. PubMed
Armstrong VL, Rakoczy S, Rojanathamannee L, and Brown-Borg HM (2014) Expression of DNA methyltransferases are influenced by growth hormone in the long living Ames dwarf mouse. Journals of Gerontology Series A: Biological Sciences and Medical Sciences 69(8): 923-933. doi:10.1093/gerona/glt133. PubMed

2013

Romanick MA, Thompson LV, and Brown-Borg HM (2013) Murine models of atrophy, cachexia and sarcopenia in skeletal muscle. Biochimica et Biophysica Acta. 1832:1410-1420. doi:10.1016/j.bbadis.2013.03.011. PubMed
Brown-Borg HM and Borg KE (2013) A summary of the proceedings of the Eleventh International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 29-August 3, 2012. Experimental Gerontology 48(7):593-595. PubMed
Brown-Borg HM and Rakoczy S (2013) Metabolic adaptations to short-term every other day feeding in long-living Ames dwarf mice. Experimental Gerontology 48:905-919. doi.org/10.1016/j.exger.2013.06.009. PubMed

2012

Brown-Borg HM and Bartke A (2012) GH and IGF1: Roles in energy metabolism of long-living GH mutant mice. J. Gerontology Series A: Biological Sciences and Medical Sciences 67(6):652-660 doi: 10.1093/Gerona/gls086. PMC3348496. PubMed
Anisimov VN, Bartke, A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg HM, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, Kennedy B, Konovalenko M, Kraemer B, Moskalev A, Petropoulos I, Pasyukova E, Rattan S, Rogina B, Seluanov A, Shaposhnikov M, Shmookler Reis R, Tavernarakis N, Vijg J, Yashin A, and Zimniak P (2012) The second international conference on ‘genetics of aging and longevity’. Aging 4(5):305-317. PubMed
Traustadottir T, Davies SS, Su Y, Choi L, Brown-Borg HM, Roberts JL II, and Harman SM (2012) Oxidative stress in older adults: Effects of physical fitness. AGE 34:969-982. doi:10.1007/s11357-011-9277-6. PubMed
Brown-Borg HM, Johnson WT, and Rakoczy S (2012) Expression of oxidative phosphorylation components in mitochondria of long-living Ames dwarf mice. AGE 34(1):43-57. doi:10.1007/s11357-011-9212-x. PMID 3260352. PubMed

2011

Morrissey MB, Brown-Borg HM, de Cabo R, and Silverstein M (2011) An interdisciplinary look at advancing pain care, education and research: Responding to the IOM’s call to action to improve pain management. From Publication to Practice – The Gerontological Society of America pp. 1-4.
Sharma S, Darland D, Lei S, Rakoczy S, and Brown-Borg HM (2011) NMDA and kainate receptor expression, long-term potentiation and neurogenesis in long-lived Ames dwarf mice. AGE. 34(3):609-620 doi:10.1007/s11357-011-9253-1. PMC3337943. PubMed
Brown-Borg HM and Borg KE (2011) A summary of the proceedings of the Tenth International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 25-30, 2010. Experimental Gerontology Vol. 46 Issues 2-3. PMC3159923. PubMed
Derenne A, Brown-Borg HM, Feltman K, Corbett G, and Lackman S (2011) Acquisition of steady-state operant behavior in long-living Ames dwarf mice. Physiology and Behavior 104(5):1048-1052. doi:10.1016/j.physbeh.2011.07.006. PubMed

2010

Sharma S, Haselton J, Rakoczy SG, Branshaw S, and Brown-Borg HM (2010) Spatial memory is enhanced in long-living Ames dwarf mice and maintained following kainic acid induced neuronal loss. Mechanisms of Ageing & Development 131(6):422-435 doi:10.1016/j.mad.2010.06.004. PubMed
Sharma S, Rakoczy SG, and Brown-Borg HM (2010) Assessment of spatial memory in mice. Life Sciences 87(17-18):521-536. doi:10.1016/j.lfs.2010.09.004. PubMed
Sharma S, Rakoczy SG, Dahlheimer K, and Brown-Borg HM (2010) The hippocampus of Ames dwarf mice is resistant to kainic acid-induced oxidative stress. Experimental Gerontology 45:936-949. PubMed
Vallanat B, Anderson SP, Brown-Borg HM, Ren H, Jonnalagadda S, Srinivasan R, and Corton JC (2010) Analysis of the heat shock response in the mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor a (PPARa). BMC Genomics 11:16-24. PMC2823686. PubMed
Ren H, Vallanat B, Brown-Borg HM, Currie R, and Corton JC (2010) Regulation of proteome maintenance gene expression by activators of peroxisome proliferator-activated receptor a. PPAR Research 2010; 2010:727194. doi10.1155/2010/727194 PMC3026993. PubMed
Chen C, Brown-Borg HM , Rakoczy S, Ferrington D, and Thompson LV (2010) Aging impairs the expression of glutamate cysteine ligase catalytic subunit in soleus muscle under stress. J. Gerontology: Biological Sciences 65(2):129-137. doi: 10.1093/gerona/glp194. PMC2806238. PubMed

2009

Brown-Borg HM (2009) Hormonal control of aging in rodents: The somatotropic axis. Molecular and Cellular Endocrinology 299(1):64-71. PubMed
Brown-Borg HM, Rakoczy SG, Sharma S, and Bartke A (2009) Long-living growth hormone receptor knock out mice: potential mechanisms of altered stress resistance. Experimental Gerontology 44:10-19. PMC2743895. PubMed

2008

Dhanasekaran M, Karuppagounder SS, Uthayathas S, Wold L, Parameshwaran K, Babu J, Suppiramaniam V, and Brown-Borg H (2008) Effect of dopaminergic neurotoxin MPTP/MPP+ on coenzyme Q content. Life Sciences 83:92-95. ScienceDirect
Chen C, Brown-Borg HM, Rakoczy SG, and Thompson LV (2008) Muscle disuse: adaptation of antioxidant systems is age-dependent. J Gerontology: Biological Sciences 63A(5):461-466. PMC2670877. PubMed
Shavali S, Brown-Borg HM, Ebadi M, and Porter J (2008) Mitochondrial localization of alpha-synuclein protein in alpha-synuclein-overexpressing cells. Neuroscience Letters 439(2):125-128. PMC2502066. PubMed
Dhanasekaran M, Albano CB, Pellet L, Karuppagounder SS, Uthayathas S, Suppiramaniam V, Brown-Borg HM, and Ebadi M (2008) Role of lipoamide dehydrogenase and metallothionein on 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced toxicity. Neurochemical Research 33(6):980-984. PubMed
Schrag M, Sharma S, Brown-Borg HM, and Ghribi O (2008) Hippocampus of Ames dwarf mice is resistant to b-amyloid-induced tau hyperphosphorylation and changes in apoptosis-regulatory protein levels. Hippocampus 18(3):239-244. PubMed

2006-2007

Brown-Borg HM (2007) Hormonal regulation of longevity in mammals. Ageing Research Reviews 6:28-45. PMC1978093. PubMed
Brown-Borg HM (2006) Longevity in mice: Is stress resistance a common factor? AGE 28:145-162. PMC2464727. NCBI
Uthus EO and Brown-Borg HM (2006) Methionine flux to transsulfuration is enhanced in the long living Ames dwarf mouse. Mechanisms of Ageing & Development 127:444-450. PMC2014095. NCBI
Dhanasekaran M, Uthayathas S, Karuppagounder SS, Parameshwaran K, Suppiramaniam V, Ebadi M, and Brown-Borg HM (2006) Ebselen effects on MPTP-induced neurotoxicity. Brain Research 1118:251-254. ScienceDirect
Johnson WT and Brown-Borg HM (2006) Cytochrome c oxidase deficiency occurs in cardiac mitochondria during late postnatal heart development in progeny of copper-deficient dams. Experimental Biology and Medicine 231:172-180. AGRIS
Tharakan B, Muralikrishnan D, Brown-Borg HM, and Manyam BV (2006) Trichopus zeylanicus combats fatigue without amphetamine-mimetic activity. Phytotherapy Research 20:165-168. PubMed
Brown-Borg HM and Corton JC (2006) PGC-1, calorie restriction and aging. American Aging Association Newsletter May 2006. PubMed
Ebadi M, Brown-Borg HM, Sharma S, Shavali S, El ReFaey H, and Carlson EC (2006) Therapeutic efficacy of selegiline in neurodegenerative disorders and neurological diseases. Current Drug Targets 7:1513-1529. PubMed

2005

Brown-Borg HM and Rakoczy SG (2005) Glutathione metabolism in long-living Ames dwarf mice. Experimental Gerontology 40(1-2):115-120. PubMed
Corton JC and Brown-Borg HM (2005) Peroxisome proliferator-activated receptor gamma co-activator 1 (PGC-1) in caloric restriction and other models of longevity. J. Gerontology: Biological Sciences 60A (12):1494-1509. PubMed
Brown-Borg HM, Rakoczy SG, and Uthus EO (2005) Growth hormone alters methionine and glutathione metabolism in Ames dwarf mice. Mechanisms of Ageing & Development 126(3):389-398. PubMed
Stauber AJ, Brown-Borg HM, Liu J, Waalkes MP,Laughter A, Staben RA, Coley JC, Swanson C, Voss KA, Kopchick JJ, and Corton JC (2005) Constitutive expression of peroxisome proliferator-activated receptor a-regulated genes in dwarf mice. Molecular Pharmacology 67(3):681-694. PubMed
Ebadi M, Sharma S, Ghafourifar P, Brown-Borg H, and El ReFaey H (2005) Peroxynitrite in the pathogenesis of Parkinson’s disease and the neuroprotective role of metallothioneins. Methods in Enzymology 396:276-298. PubMed
Ebadi M, Brown-Borg HM, El Refaey H, Singh B, Garrett S, Shavali S, and Sharma SK (2005) Metallothionein-mediated neuroprotection in genetically engineered mouse models of Parkinson’s disease. Brain Research: Molecular Brain Research 134:67-75. PubMed

2004

Brown-Borg HM, Rakoczy SG, and Uthus EO (2004) Growth hormone alters components of the glutathione metabolic pathway in Ames dwarf mice. Annals of the New York Academy of Sciences 1019:317-320. PubMed
Brown-Borg HM (2004) Antiaging supplement holds promise to halt age-related cognitive deterioration. Exp. Biol. Med. 229(5):367-368. SAGEJournals
Fan LQ, Brown-Borg H, Brown S, Edwards RJ, and Corton JC (2004) Regulation of phase I and phase II steroid metabolism enzymes by PPARa activators. Toxicology 204(2-3):109-121. PubMed
Fan LQ, Brown-Borg H, Brown S, Westin S, Mode A, and Corton JC (2004) PPARalpha activators down-regulate CYP2C7, a retinoic acid and testosterone hydroxylase. Toxicology 203(1-3):41-48. PubMed
Esquifino AI, Arce A, Alvarez MP, Chacon F, Brown-Borg H, and Bartke A (2004) Differential effects of light/dark recombinant h-prolactin administration on the submaxillary lymph nodes and spleen activity of adult male mice. Neuroimmunomodulation 11(2):119-126. Karger
Muralikrishnan D, Ebadi M, and Brown-Borg HM (2004) Dopamine agonist 3-PPP fails to protect against MPTP-induced toxicity. Neurochemical Research 29(2):379-384. Springer
Romanick MA, Rakoczy SG, and Brown-Borg HM (2004) Long-lived Ames dwarf mouse exhibits increased antioxidant defense in skeletal muscle. Mechanisms of Ageing Development 125(4):269-281. PubMed
Esquifino AI, Arce A, Alvarez MP, Jimenez V, Brown-Borg H, and Bartke A (2004) Light/dark h-prolactin effects on the submaxillary lymph nodes and spleen activity of Ames dwarf mice. Experimental Biology and Medicine (in press).

2003

Brown-Borg HM (2003) Hormonal regulation of aging and life span. Trends Endocrinol. Metab. 14(4):151-153. PubMed
Atwood CS, Barzilai N, Brown-Borg HM, Jarrard DF, Fu VX, Heilbronn LK, Ingram DK, Ravussin E, Schwartz RS, and Weindruch R (2003) Pennington Scientific Symposium on Mechanisms and Retardation of Aging. Experimental Gerontology 38:1217-1226. PubMed
Uthus EO and Brown-Borg HM (2003) Altered methionine metabolism in long-living Ames dwarf mice. Experimental Gerontology 38:491-498. PubMed
Kennedy MA, Rakoczy SG, and Brown-Borg HM (2003) Long living Ames dwarf mouse hepatocytes readily undergo apoptosis. Experimental Gerontolog 38:997-1008. PubMed
Brown-Borg HM and Rakoczy SG (2003) Growth hormone administration to long-living dwarf mice alters multiple components of the antioxidative defense system. Mechanisms of Ageing and Development 124:1013-1024. PubMed
Ren J, Roughead ZK, Norby FL, Rakoczy S, Wold LE, Mabey RL, and Brown-Borg HM (2003) Increases in insulin-like growth factor-1 level and peroxidative damage after gestational ethanol exposure in rats. Pharmacological Research 47(4):341-347. PubMed

2002

Esquifino AI, Arce A, Alvarez MP, Szary A, Brown-Borg H, and Bartke A (2002) Effects of overexpression of growth hormone on T cell activity in transgenic mice. J. Physiol. Biochem. 58(3):161-168. PubMed
Brown-Borg HM, Rakoczy SG, Romanick MA, and Kennedy MA (2002) Effects of growth hormone and insulin like growth factor-1 on hepatocyte antioxidative enzymes. Exp. Biol. Med. 227(2):94-104. PubMed
Muralikrishnan D, Ebadi M, and Brown-Borg HM (2002) Effect of MPTP on dopamine metabolism in Ames dwarf mice. Neurochemical Research 27(6):457-464. PubMed
Ren J and Brown-Borg HM (2002) Impaired cardiac excitation-contraction coupling in ventricular myocytes from Ames dwarf mice with growth hormone/insulin-like growth factor I deficiency. Growth Hormone and IGF Research 12: 99-105. PubMed
Colligan PB, Brown-Borg HM, Duan J, Ren BH, and Ren J (2002) Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice. J. Endocrinology 173:257-264. PubMed

2000-2001

Brown-Borg HM, Johnson WT, Rakoczy SG, and Romanick MA (2001) Mitochondrial oxidant production and oxidative damage in Ames dwarf mice. J. Am. Aging Assoc. 24(3):85-96. PubMed
Bartke A, Brown-Borg H, Mattison J, Kinney B, Hauck S, and Wright C (2001) Prolonged longevity of hypopituitary dwarf mice. Experimental Gerontology 36(1):21-28. PubMed
Brown-Borg HM and Rakoczy SG (2000) Catalase expression in delayed and premature aging mouse models. Experimental Gerontology 35(2):199-212. PubMed
Bartke A, Brown-Borg HM, Kinney B, Mattison J, Wright C, Hauck S, Coschigano K, and Kopchick J (2000) Growth hormone and aging. J. Am. Aging. Assoc. 23:219-225. PubMed

1997-1999

Brown-Borg HM, Bode AM, and Bartke A (1999) Antioxidative mechanisms and plasma growth hormone levels: potential relationship in the aging process. Endocrine 11(1):41-48. PubMed
Dialynas E, Brown-Borg HM, and Bartke A (1999) Immune function in transgenic mice overexpressing growth hormone (GH) releasing hormone, GH or GH antagonist. Proc. Soc. Exp. Biol. Med. 221(3):178-183. PubMed
Bartke A, Brown-Borg HM, Bode AM, Carlson J, Hunter WS, and Bronson RT (1998) Does growth hormone prevent or accelerate aging? Experimental Gerontology. 33:675-687. PubMed
Brown-Borg HM, Blecha F, and Klemcke HG (1997) Influence of plasma prolactin concentrations and age on neonatal immune function. Comp. Biochem. Phys. 118A(3):821- 829. ScienceDirect

1995-1996

Brown-Borg HM, Borg KE, Meliska CJ, and Bartke A (1996) Dwarf mice and the aging process. Nature 384:33. Nature
Brown-Borg HM, Zhang FP, Huhtaniemi I, and Bartke A (1996) Developmental onset of prolactin receptor gene expression in fetal and neonatal mice. Eur. J. Endo. 134(6):751-757. PubMed
Esquifino AI, Szary A, Brown-Borg HM, and Bartke A (1996) Age-related effects of ectopic pituitary transplants on the activation of Ames dwarf mouse lymphocytes in vitro. Proc. Soc. Exp. Bio. Med. 211:87-93. PubMed
Klemcke HG, Brown-Borg HM, and Borg KE (1995) Functioning of the porcine pituitary-adrenocortical axis during neonatal development. Biology of the Neonate 67:274-286. PubMed
Borg KE, Brown-Borg HM, and Bartke A (1995) Assessment of the primary adrenal cortical and pancreatic hormone basal levels in relation to plasma glucose and age in the unstressed Ames dwarf mouse. Proc. Soc. Exp. Bio. Med. 210(2):126-133. PubMed

1991-1993

Brown-Borg HM, Klemcke HG, and Blecha F (1993) Lymphocyte proliferative responses in neonatal pigs with high or low plasma cortisol concentration after stress induced by restraint. Am. J. Vet. Res. 54(12):2015-2020. PubMed
Brown-Borg HM, Klemcke HG, Borg KE, and Klindt J (1993) Prolactin and growth hormone clearance in neonatal boars. J. Ani. Sci. 71:2055-2060. PubMed
Klemcke HG, Lunstra DD,Brown-Borg HM, Borg KE, and Christenson RK (1993) Association between low birthweight and increased adrenocortical function in neonatal pigs. J. Ani. Sci. 71:1010-1018. PubMed
Brown-Borg HM and Edens FW (1992) In vivo neurotoxin administration alters immune responses in chickens. Comp. Biochem. Phys. 102C(1):177-183. ScienceDirect
Brown-Borg HM and Edens FW (1991) Tissue monoamine and plasma corticosterone concentrations following sympathetic alteration during acute endotoxicosis in chickens. Comp. Biochem. Phys. 99C(3):547-554. Catecholamine- and endotoxin-influenced cutaneous basophil hypersensitivity in chickens. Comp. Biochem. Phys. 99C(3):541-545. PubMed
Edens FW, May JD, Yersin AG, and Brown-Borg HM (1991) Effect of fasting on plasma thyroid and adrenal hormone levels in turkey poults infected with Bordetella avium. Avian Dis. 35(2):344-347. PubMed

1986-1987

Beck MM, Brown-Borg HM, and Jones TA (1987) Peripheral and brainstem auditory function in paroxysmal (px) White Leghorn chicks. Brain Research 406:93-98. ScienceDirect
Brown-Borg HM, Beck MM, and Jones TA (1987) Origins of peripheral and brainstem auditory responses in the White Leghorn chick. Comp. Biochem. Phys. 88A (3):391-396. PubMed
Jones TA, Beck MM, and Brown-Borg HM (1987) Far-field recordings of short latency auditory responses in the White Leghorn chick. Hearing Research 27(1):67-74.
Brown-Borg HM, Beck MM, and Jones TA (1986) Influence of stimulus polarity on auditory responses in the chick. J. Auditory Res. 26:255-260.

Books, Chapters, Special Issues

Brown-Borg HM and Borg KE (eds) (2015) Special Issue: Proceedings of the Twelfth International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 27-August 1, 2014. Experimental Gerontology Vol 68 pp. 1-106.
Brown-Borg HM (2014) Endocrinology of aging and longevity. Reference Module in Biomedical Sciences. Elsevier Press, Oxford. doi:10.1016/B978-0-12-801238-3.00151-3.
Brown-Borg HM and Borg KE (eds.) (2013) Special Issue: Proceedings of the Eleventh International Symposium on Neurobiology and Neuroendocrinology of Aging. Experimental Gerontology Vol. 48 Issue 7 pp. 593-700.
Brown-Borg HM, Hale B, Anderson R, McCarter R, Morley J, Musi N, Olshansky J, St Jacques P, Walston J, and Willcox B (2012) Nutrition in aging and disease: Update on the biological sciences. Aging Health 8(1):13-16.
Brown-Borg HM (2011) Role of the somatotropic axis in mammalian aging. Chapter 2. In: Handbook of the Biology of Aging. Masoro E, Austad S (eds). 7th Edition. pp 25-45.
Brown-Borg HM and Borg KE (eds.) (2011) Special Issue: Proceedings of the Tenth International Symposium on Neurobiology and Neuroendocrinology of Aging. Experimental Gerontology Vol. 46 Issues 2-3.
Everitt A, Brown-Borg HM, Le Couteur DG, and Bartke A (2010) Food Restriction, Hormones, Genes and Aging. Chapter 12. In: Calorie Restriction, Aging and Longevity. Eds. Everitt AV, Rattan SIS, Le Couteur DG, and de Cabo R. Springer, New York, NY. pp. 217-232.
Everitt AV, Heilbronn LK, Morris BJ, Brown-Borg HM, Merry BJ, Simpson SJ, Varady KA, Masoro EJ, Redman LM, and Le Couteur DG (2010) Conclusion: Human calorie restriction and anti-aging therapy. Chapter 18. In: Calorie Restriction, Aging and Longevity. Eds. Everitt AV, Rattan SIS, Le Couteur DG, and de Cabo R. Springer, New York, NY. pp. 311-318.
Sell C, Lorenzini A, and Brown-Borg HM (eds.) (2009) A Critical Analysis of Lifespan Extension: From Single Cell Organisms to Man. Humana Press, New York, NY.
Brown-Borg HM, Sharma S, Borg KE, and Rakoczy SG (2009) Growth hormone and aging in rodents, Chapter 7 In: A Critical Analysis of Lifespan Extension. Eds. Sell C, Lorenzini A, and Brown-Borg HM. Humana Press, New York, NY. pp. 115-130.
Brown-Borg HM (2005) Aging and Life Span. In: The Growth Hormone/Insulin-like Growth Factor Axis During Development. Advances in Experimental Medicine and Biology Eds. Varelo-Nieto I, Chowen JA. Chapter 11. Springer, New York, NY. Volume 567 pp. 259-283.
Bartke A and Brown-Borg HM (2004) Life extension in the dwarf mouse, In: Current Topics in Developmental Biology, Ed. Schatten GP. Chapter 6. Elsevier Academic Press, San Diego, CA. Volume 63 pp. 189-225.
Brown-Borg HM and Harman SM (2003) Hormones and Oxidative Stress, In: Oxidative stress and aging: advances in basic science, diagnostics, and intervention, Eds. Cutler RG and Rodriguez H. Chapter 61, World Scientific Publishing, River Edge, NJ, pp. 1070-1119.