Publications

2018

Casselli T, Tourand Y, Scheidegger A, Arnold W, Proulx A, Stevenson B, Brissette CA (2018) DNA methylation by restriction modification systems affects the global transcriptome profile in Borrelia burgdorferi. J Bacteriol. pii: JB.00395-18. doi: 10.1128/JB.00395-18. PubMed
Arnold WK, Lethbridge KG, Savage CR, Smith 2nd, TC, Brissette CA, Seshu J, Stevenson B, (2018) Transcriptomic insights on the virulence-controlling CsrA, BadR, RpoN, and RpoS regulatory networks in the Lyme disease spirochete. PLoS One 13(8):e0203286. doi: 10.1371/journal.pone.0203286. PLoS One
Divan A, Casselli T, Narayanan SA, Mukherjee S, Zawieja DC, Watt JA, Brissette CA, Newell-Rogers, MK (2018) Borrelia burgdorferi adhere to blood vessels in the dura mater and are associated with increased meningeal T cells during murine disseminated borreliosis. PLoS One 13(5):e0196893. doi: 10.1371/journal.pone.0196893. PubMed
Greenmyer J, Gaultney RA, Brissette CA, Watt JA (2018) Primary human microglia are phagocytically active and respond to Borrelia burgdorferi with upregulation of chemokines and cytokines. Front Microbiol. 9:811. doi: 10.3389/fmicb.2018.00811. PubMed
Savage CR, Jutras BL, Bestor A, Tilly K, Rosa PA, Tourand Y, Stewart PE, Brissette CA, Stevenson B (2018) Borrelia burgdorferi SpoVG DNA- and RNA-binding protein and its transcript affect the physiology of the Lyme disease spirochete. J 2018 pii: JB.00033-18. doi: 10.1128/JB.00033-18. PubMed

2017

Brissette CA (2017) burgdorferi Enolase and Plasminogen Binding. In Moonlighting Proteins: Novel Virulence Factors in Bacterial Infection. B. Henderson (ed) J. Wiley & Sons, Inc., Hoboken, N.J. pg. 291-301
Condry DLJ, Bradley DS, Brissette CA (2017) Designing a Lyme disease vaccine as a tool to teach basic concepts in microbiology and immunology in a graduate interdisciplinary, active learning module. J Microbiol Biol Educ.18(3). pii: 18.3.52. doi: 10.1128/jmbe.v18i3.1304. PubMed
Stone BL, Tourand Y, Brissette CA (2017) Brave New Worlds: The Expanding Universe of Lyme Disease. Vector Borne and Zoonotic Diseases. 17(9):619-629. DOI:10.1089/vbz.2017.2127. PubMed
Stone BL, Brissette CA (2017) Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to lead studies for Borrelia miyamotoi. Front Immunol 8:12. doi: 103389/fimmu.2017.00012. PubMed
Casselli T, Qureshi H, Peterson E, Perley D, Blake E, Jokinen B, Abbas A, Nechaev S, Watt JA, Dhasarathy A*, Brissette* CA (2017) MicroRNA and mRNA transcriptome profiling in primary human astrocytes infected with Borrelia burgdorferi. PLoS One 12(1):e0170961. doi: 10.1371/journal.pone.0170961. PubMed *Co-corresponding authors

2015-2016

Arnold WK, Savage CR, Brissette CA, Seshu J, Livny J, and Stevenson B (2016) RNA-Seq of Borrelia burgdorferi in multiple phases of growth reveals insights into the dynamics of gene expression and transcriptome architecture. PLoS One 11(10):e0164165. doi: 10.1371/journal.pone.0164165. PubMed
Stone BL and Brissette CA (2016) Laboratory Cultivation and Maintenance of Borrelia miyamotoi. Current Protocols in Microbiology. 12;42:12F.1.1-6. doi: 10.1002/cpmc.12. PubMed
Gonzalez T, Gaultney RA, Floden AM, and Brissette CA (2015) Escherichia coli lipoprotein binds human plasminogen via an intramolecular domain. Frontiers Microbiol 6:1095. doi: 10.3389/fmicb.2015.01095 PubMed
Byram R, Gaultney RA, Floden AM, Hellekson C, Stone BL, Bowman A, Stevenson B, JohnsonJB, and Brissette CA (2015) Borrelia burgdorferi RevA significantly affects pathogenicity and host response in the mouse model of Lyme disease. Infect Immun 83(9):3675-83. PubMed
Stone BL, Russart M, Gaultney RA, Floden AM, Vaughan JA, and Brissette CA (2015) The western progression of Lyme disease: Infectious and non-clonal Borrelia burgdorferi sensu lato populations in Grand Forks County, North Dakota. Appl Environ Microbiol 81(1):48-58. 25304515
Petnicki-Ocwieja T and Brissette CA (2015) Lyme Disease: recent advances and perspectives. Front Cell Infect Microbiol 5(27). doi:10.3389/fcimb.2015.00027. PubMed
Claycombe KJ, Brissette CA, and Ghribi O (2015) Epigenetics of inflammation, maternal infection, and nutrition. J Nutrition 145: 1S-7S. PubMed

2013-2014

Brissette CA and Gaultney RA (2014) That’s my story, and I’m sticking to it- an update on B. burgdorferi adhesins. Front Cell Infect Microbiol doi: 10.3389/fcimb.2014. PubMed
Gaultney RA, Gonzalez T, Floden AM, and Brissette CA (2013) BB0347, from the Lyme disease spirochete Borrelia burgdorferi, is surface exposed and binds human fibronectin via the CS1 heparin-binding domain. PLoS ONE 8(9):e75643. PubMed
Brissette CA, Kees ED, Burke M, Gaultney RA, Floden AM, and Watt JA (2013) The multifaceted responses of primary human astrocytes and brain microvascular endothelial cells to the Lyme disease spirochete, Borrelia burgdorferi. ASN Neuro 5(3). doi:pii: e00119. PubMed
Floden AM, Gonzalez T, Gaultney RA, and Brissette CA(2013) Evaluation of RevA, a fibronectin binding protein of Borrelia burgdorferi, as a potential vaccine candidate for Lyme disease. Clin Vac Immunol 20(6): 892:899. PubMed

2011-2012

Bykowski T, Verma A, Brissette CA and Stevenson B (2012) Aseptic In Current Protocols in Essential Laboratory Techniques, Second Edition. S. Gallagher and E. Wiley (eds.) J. Wiley & Sons, Hoboken, N.J. 4.1.1-12.
Brissette CA, Houdek HM, Floden AM, and Rosenberger TA (2012) Acetate supplementation reduces microglia activation and brain interleukin-1beta levels in a rat model of Lyme neuroborreliosis. J Neuroinflammation 9:249. PubMed
Jutras BL, Bowman A, Brissette CA, Adams C, Chenail A, and Stevenson B* (2012) EbfC (YbaB) is a new type of bacterial nucleoid-associated protein, and a global regulator of gene expression in the Lyme disease spirochete, Borrelia burgdorferi. J Bacteriol 194 (13): 3395-406. PubMed
Jutras BL, Verma A, Adams CA, Brissette CA, Burns LH, Whetstine CR, Bowman A, Chenail AM, Zückert WR, and Stevenson B (2012) BpaB and EbfC DNA-binding proteins regulate production of the Lyme disease spirochete’s infection-associated Erp surface proteins. J Bacteriol 194(4): 778-786. PubMed
Floden AM, Watt JA, and Brissette CA (2011) Borrelia burgdorferi enolase is a surface-exposed plasminogen binding protein. PLoS ONE 6(11): e27502. PubMed

2007-2010

Brissette CA, Rossmann F, Bowman A, Cooley AE, Riley SP, Hunfeld KP, Bechtel M, Kraiczy P, and Stevenson S (2010) The borrelial fibronectin-binding protein RevA is an early antigen of human Lyme disease. Clin Vac Immunol 17(2): 274-280. PubMed
Seling A, Siegel C, Fingerle V, Jutras BL, Brissette CA, Skerka C, Wallich R, Zipfel PF, Stevenson B, and Kraiczy P (2010) Functional characterization of Borrelia spielmanii outer surface proteins that interact with distinct members of the human factor H protein family and with plasminogen. Infect Immun 78(1): 39-48. PubMed
Verma A, Brissette CA, Bowman AA, Shah ST, Zipfel PF, and Stevenson B (2010) Leptospiral endostatin-like protein A (LenA) is a bacterial cell-surface receptor for human plasminogen. Infect Immun 78:2053-2059. PubMed
Brissette CA, Bykowski T, Cooley AE, Bowman A, and Stevenson B (2009) Borrelia burgdorferi RevA antigen binds host fibronectin. Infect Immun 77(7): 2802-12. PubMed
Brissette CA, Verma A, Bowman A, Cooley AE, and Stevenson B (2009) The Borrelia burgdorferi outer-surface protein ErpX binds mammalian laminin. Microbiology 155 (Pt3): 863-72. PubMed
Brissette CA, Haupt K, Barthel D, Cooley AE, Bowman A, Skerka C, Wallich R, Zipfel PF, Kraiczy P, and Stevenson B (2009) The Borrelia burgdorferi infection-associated surface proteins ErpP, ErpA, and ErpC bind human plasminogen. Infect Immun 77(1): 300-06. PubMed
Verma A, Brissette^@CA, Bowman A, and Stevenson B (2009) Borrelia burgdorferi BmpA (antigen P39) is a laminin-binding protein. Infect. Immun. 77(11): 4940-46. PubMed @Shared first authorship.
Riley SP, Bykowski T, Cooley AE, Burns LH, Babb K, Brissette CA, Bowman A, Rotondi M, Miller MC, DeMoll E, Lim K, Fried MG, and Stevenson B (2009) Borrelia burgdorferi EbfC defines a newly-identified, widespread family of bacterial DNA-binding proteins. Nucleic Acids Res (37) 6: 1973-83. PubMed
Brissette CA, Pham TT, Coats R, Darveau RP, and Lukehart SA^.(2008) Treponema denticola does not induce production of common innate immune Mediators from primary gingival epithelial cells. Oral Microbiol Immunol 23: 474-481. PubMed
Kraiczy P, Seling A, Brissette CA, Rossmann E, Hunfeld KP, Bykowski T, Burns LH, Troese MJ, Cooley AE, Miller JC, Brade V, Wallich R, Casjens S, and Stevenson B (2008) Antibodies against Borrelia burgdorferi complement regulator -acquiring surface protein 2 (CspZ) as a serological marker of human Lyme disease. Clin Vac Immunol 15(3): 484-91. PubMed
Brissette CA, Cooley AE, Burns LH, Riley SP, Verma A, Woodman ME, Bykowski^, T and Stevenson B (2008) Lyme borreliosis spirochete Erp proteins, their known host ligands, and potential roles in mammalian infection. Int J Med Microbiol doi:10.1016/j.ijmm.2007.09.004. PubMed
Bykowski T, Woodman ME, Cooley AE, Brissette CA, Wallich R, Brade V, Kraiczy P, and Stevenson B (2008) Borrelia burgdorferi complement regulator-acquiring surface proteins (BbCRASPs): expression patterns during the mammal-tick infection cycle. Int J Med Microbiol doi:10.1016/j.ijmm.2007.10.002. PubMed
Stevenson B, Choy HA, Pinne M, Rotondi ML, Miller MC, DeMoll E, Kraiczy P, Cooley AE, Creamer TP, Suchard MA, Brissette CA, Verma A, and Haake DA (2007) Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement. PLoS ONE 2(11): e1188. PubMed
Bykowski T, Woodman ME, Cooley AE, Brissette CA, Brade V, Wallich R, Kraiczy P, and Stevenson B (2007) Coordinated expression of Borrelia burgdorferi complement regulator-acquiring surface proteins during the Lyme disease spirochete’s mammal-tick infection cycle. Infect Immun 75(9): 4227-36. PubMed
Brissette CA and Lukehart SA (2007) Mechanisms of Treponema denticola resistance to beta-defensins. Infect Immun 75(5): 2307-15. PubMed

1999-2006

Brissette CA, Simonson LG, and Lukehart SA (2004) Resistance to beta-defensins is common among oral spirochetes. Oral Microbiol Immunol 19(6): 403-7. PubMed
Brissette CA and Lukehart SA (2002) Treponema denticola is resistant to human beta-defensins. Infect Immun 70(7): 3982-4. PubMed
Mintz KP, Brissette CA, and Fives-Taylor PM (2002) A recombinase A-deficient strain of Actinobacillus actinomycetemcomitans constructed by insertional mutagenesis using a mobilizable plasmid. FEMS Microbiol Lett 206(1): 87-92. PubMed
Brissette CA and Fives-Taylor PM (1999) Actinobacillus Actinomycetemcomitans can utilize either actin dependent or actin independent mechanisms of invasion. Oral Microbiol Immunol 14(3): 137-142. PubMed
Fives-Taylor PM, Meyer DH, Mintz KP, and Brissette CA (1999) Virulence factors of Actinobacillus actinomycetemcomitans. Periodontology 2000 (20): 136-167. PubMed