Publications/Abstracts

Publications resulting from REMS projects (REMS students in bold type)

Edward C. Carlson1, Jennifer M. Teiken1, Donna I. Laturnus1, Bikash KC1, Brittany N. Berg, Shirong Zheng2, and Paul N. Podocyte-specific overexpression of metallothionein mitigates diabetic complications in the glomerular filtration barrier and glomerular histoarchitecture: a transmission electron microscopy stereometric analysis. Diabetes/Metabolism Research and Reviews. Feb;29(2):113-2 (2013).
Jangula, A., Murphy, E.J. Lipopolysaccharide-induced blood brain barrier permeability is enhanced by alpha-synuclein expression. Neuroscience Letters. Sep 13; 551: 23-27 (2013).

Carlson EC, Chhoun JM, Laturnus DI, Bikash KC, Berg B, Zheng S, Epstein PN. Podocyte-specific overexpression of metallothionein mitigates diabetic complications in the glomerular filtration barrier and glomerular histoarchitecture: a transmission electron microscopy stereometric analysis. Diabetes Metab Res Rev. Feb;29(2):113-24 (2013) .

Reisenauer, C.J., Bhatt, D.P., Mitteness, D.J., Slanczka, E.R., Gienger, H.M., Watt, J.A., and Rosenberger, T.A. Acetate supplementation attenuates lipopolysaccharide-induced neuroinflammation, J. Neurochem. 117, 264-274(2011).

Jaya Prasanthi R.P., Tyler Larson, Jared Schommer and Othman Ghribi (2011). siRNA to the growth arrest and DNA-damage-inducible protein gadd153 protects against 27-hydroxycholesterol-induced Alzheimer's disease-like pathology in rabbit hippocampus. PLoS ONE 6(10): e26420.

Sondag CM, Combs CK. Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Abeta1-40. Department of Pharmacology, Physiology & Therapeutics, Journal of Neuroinflammation, March 19; 7:22, (2010).

Chen, X., Wagener, J.F., Morgan, D.H., Hui, L., Ghribi, O. and J.D. Geiger Endolysosome Mechanisms Associated with Alzheimer's Disease-Like Pathology in Rabbits Ingesting Cholesterol-Enriched Diet. J. Alzheimer's Disease 22: 1289-1303 (2010).

Chen X, Wagener JF, Morgan DH, Hui L, Ghribi O, Geiger JD. Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet. J Alzheimers Dis.22(4):1289-303 (2010)

Frieler, R.A., Mitteness, D.J., Golovko, M.Y., Gienger, H.M., and Rosenberger, T.A. (2009) Quantitative determination of free glycerol and myo-inositol from plasma and tissue by high-performance liquid chromatography, J. Chromatography B 877, 3667-3672.

Othman Ghribi, Eric Schommer and Jaya R.P. Prasanthi (2009). 27-hydroxycholesterol as the missing link between circulating cholesterol and AD-like pathology. Alzheimer's and Dementia 5(4) Supplement 1: P180.

M. Wu, Audet A, Cusic J, Seeger D, Cocheon R, and Ghribi O. Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in rabbits fed cholesterol-rich diets. Journal of Neurochemistry (2009);111:1011-1021.

S. Kannan*, Huang H*, Seeger D*, Audet A*, Gao H, Chen Y, Li S & Wu M. (2009). Alveolar Epithelial Type II Cells Activate Alveolar Macrophages and Mitigate P. Aeruginosa Infection. PLoS ONE 4(3):e4891. PMID: 19305493

Jaya Prasanthi Rantham Prabhakara, Gwen Feist, Sarah Thomasson, Alex Thompson, Eric Schommer and Othman Ghribi. Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. Journal of Neurochemistry 107(6): 1722-1729 (2008).

Chen X, Gawryluk JW, Wagener JF, Ghribi O, Geiger JD. Caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer's disease. J Neuroinflammation. (2008) Apr 3;5:12

Chen X, Wagener JF, . Hui L, Ghribi O, Geiger JD. Endolysosome mechanisms associated with Alzheimer's disease-like pathology in rabbits ingesting cholesterol-enriched diet. J Alzheimers Dis. 2010;22(4):1289-303

S. Kannan, Audet A, Huang H, Chen LJ & Wu M. 2008. Cholesterol-rich lipid membrane and Lyn are required for alveolar macrophage phagocytosis during Pseudomonas aeruginosa infection. J Immunol 180:2396-2408. PMID: 18250449

Chen, X., Gawryluk, J.W., Wagener, J.F., Ghribi, O., and J.D. Geiger. (2008) Caffeine Blocks Dysruption of Blood Brain Barrier in a Rabbit Model of Alzheimer's Disease. Journal of Neuroinflammation 5: 12 (Most highly accessed designation)
S Kannan, A Audet, J Knittel, S Mullegama, and M Wu. (2006). Src tyrosine kinase Lyn plays a role in P aeruginosa infection of respiratory epithelium cells. European J Immunol 36:1739-1752. PMID: 16791881

Carr, P.A., Roller,.M.J. and Zaruba, R.A. Peptidergic input to immunohistochemically-identified Renshaw cells. Brain Research 887 (2000) 194-198.

Published Abstracts (National Meetings, REMS students in bold type)

Reisenauer, C.J., Mitteness, D.J., Slanczka, E.R., Gienger, H.M., Rosenberger, T.A. (2009) Glyceryl triacetate increases tissue acetyl-CoA levels and attenuates cholinergic cell loss in a rat model of neuroinflammation, American Society for Neurochemistry, Charleston, SC.

Bhatt, D.P., Mitteness, D.J., Gienger, H.M., Rosenberger, T.A. (2010) Acetate supplementation reduces neuroglia activation and cholinergic cell loss while increasing brain energy reserves and lipid deposition in a rat model of neuroinflammation, Glia in Health and Disease, Cold Spring Harbor, NY.

Thad A. Rosenberger, C. J. Reisenauer, D. J. Mitteness, E. R. Slanczka, A. Ajjimaporn, and H. M. Gienger (2009) Glyceryl Triacetate Increases Tissue Acetyl-CoA Levels and Attenuates Cholinergic Cell Loss in a Rat Model of Neuroinflammation, IDeA Conference, Bethesda, Maryland.

Jonathan D. Geiger, John F. Wagener, Daniel H. Morgan, Othman Ghribi, and Xuesong Chen. Cholesterol-enriched diet induces endosome/lysosome dysfunction in a rabbit model of sporadic Alzheimer's disease. American Society for Neurochemistry meeting 2009
Xuesong Chen, John F. Wagener, Othman Ghribi, and Jonathan D. Geiger. Cholesterol-enriched diet induces endosome/lysosome dysfunction in a rabbit model of inclusion body myositis. Experimental Biology Meeting 2009
Xuesong Chen, John F. Wagener, Daniel H. Morgan, Othman Ghribi, and Jonathan D. Geiger. Endosome and lysosome dysfunction underlies cholesterol-enriched diet-induced AD-like pathology in rabbits. Society For Neuroscience Meeting 2009.
Xuesong Chen, John F. Wagener, Daniel H. Morgan, Othman Ghribi, and Jonathan D. Geiger. Endosome and lysosome dysfunction underlies cholesterol-enriched diet-induced AD-like pathology in rabbits. Society For Neuroscience Meeting 2009

Abstracts (Local Meetings, REMS students in bold type)

Dane J. Mitteness, Ryan A. Frieler, Mikhail Y. Golovko, Heidi M. Gienger and Thad A. Rosenberger, (2009) Quantitative determination of free glycerol and myo-inositol from plasma and tissue by high-performance liquid chromatography, Frank Low Research Day.

Chris J. Reisenauer, Dane J. Mitteness, Evan R. Slanczka, Ampornpan Ajjimaporn, Heidi M. Gienger, and Thad A. Rosenberger (2009) Glyceryl triacetate increases tissue acetyl-CoA levels and attenuates cholinergic cell loss in a rat model of neuroinflammation, Frank Low Research Day.

Dhaval P. Bhatt, Dane J. Mitteness, Heidi M. Gienger, and Thad A. Rosenberger (2010) Acetate Supplementation Increases Rat Brain Energy Reserves, Frank Low Research Day.

Zachary B. Castor, Dane J. Mitteness, Dhaval P. Bhatt, Heidi M. Gienger, and Thad A. Rosenberger (2010) Acetate Supplementation Increases Saturated Fatty Acid and Ether Phospholipid Content in Rat Brain, Summer REU Student Presentations.

Dhaval P. Bhatt, Heidi M. Gienger, Dane J. Mitteness, John A. Watt, and Thad A. Rosenberger (2011) Increasing Rat Brain Energy Reserves: a Potential Mechanism for the Neuroprotective and Anti-Inflammatory effects of Acetate Supplementation, Graduate Scholarly Forum.

Daniel H. Morgan, Xuesong Chen, Othman Ghribi and Jonathan D. Geiger. Effects of a cholesterol-enriched diet on blood-testis barrier integrity in rabbits. Frank Low Research Day (2009) at SMHS

Xuesong Chen, John F. Wagener, Daniel H. Morgan, Othman Ghribi, and Jonathan D. Geiger. Cholesterol-enriched diet induces endosome/lysosome dysfunction in a rabbit model of sporadic Alzheimer's disease. Frank Low Research Day (2009).
John F. Wagener, Xuesong Chen, Othman Ghribi and Jonathan D. Geiger. Endosome/Lysosome Dysfunction in a Rabbit Model for Inclusion Body Myositis. Frank Low Research Day (2009).
Dane J. Mitteness, Heidi M. Gienger, and Thad A. Rosenberger. Lipopolysaccharide induces a selective and dose-dependent increase in the turnover rates of brain arachidonic acid in rats subjected to neuroinflammation, Frank Low Research Day (2011).