Welcome to Nechaev lab!
The lab pursues the mechanisms that enable epigenetic regulation of gene activity. The puzzling problem is how the same genome is properly read in each cell and how malfunctioning of this mechanism can lead to cancer. We believe that a phenomenon of RNA polymerase II pausing has something to do with it.
03/2018 - Sergei receives a 5-year NSF CAREER grant to study the molecular mechanisms of global transcription regulation at gene promoters.
02/2018 - Damien Parrello joins the lab as a postdoctoral fellow.
09/2017 - Sergei receives a 3-year R21 grant for the development of small RNA-based technology to analyze degraded cancer specimens.
04/2017 - Ann Samarakkody accepts a postdoctoral position at Boston Children's Hospital, Harvard Medical School.
03/21/2017 - Ann Samarakkody
defends her PhD thesis. Congratulations Dr Samarakkody!
02/2017 - Ata Abbas accepts a position of Adjunct Assistant Professor at Cleveland Clinic Lerner College of Medicine, Cleveland, OH
12/2016 - Ann Samarakkody presents permanganate footprinting technique at UC Boulder, Taatjes Lab
Recent publications from the lab:Scheidegger et al., 2015 . Samarakkody et al., 2015. Link to the UND news article.
Recent collaborative publications: