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The latest published papers

Sukumaran P, Schaar A, Sun Y, Singh BB .Functional role of TRP channels in modulating ER stress and Autophagy. Cell Calcium . 2016 Aug;60(2):123-32. doi: 10.1016/j.ceca.2016.02.012. Epub 2016 Mar 11. Review.

Stone BL, Brissette, CA . Cultivation and Laboratory Maintenance of Borrelia miyamotoi. Current Protocols in Microbiol . 12;42:12F.1.1-6. doi: 10.1002/cpmc.12.2016 Aug.

Li X, He S, Zhou X, Li R, Zhang S, Yu M, Ye Y, Wang Y, Li G, Huang C, and Wu M. Pseudomonas aeruginosa infection augments inflammation through miR-301b repression of c-Myb-mediated immune activation and infiltration. Nature Microbiology , Article number: 16132 (2016), doi:10.1038/nmicrobiol.2016.132   

Chella Krishnan K, Mukundan S, Alagarsamy J, Hur J, Nookala S, Siemens N, Svensson M, Hyldegaard O, Norrby-Teglund A, Kotb MGenetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse  PLoS Pathog . 2016 Jul 11;12(7):e1005732. doi: 10.1371/journal.ppat.1005732. eCollection 2016 Jul.

Arnold, W.K., Savage, C.R., Brissette, C.A. , Seshu, J., Livny, J., and B. Stevenson (2016). RNA-Seq of Borrelia burgdorferi in multiple phases of growth reveals insights into the dynamics of gene expression and transcriptome architecture.  PLoS One . 2016 Oct 5;11(10):e0164165. doi: 10.1371/journal.pone.0164165. 

Brissette, C.A . B. burgdorferi Enolase and plasminogen binding. In Moonlighting Proteins: Novel virulence factors in bacterial infection. B. Henderson (ed) Wiley/Blackwell . In Press.

Li S, Geiger NH, Soliman ML, Hui L, Geiger JD, Chen X (2015) Caffeine, Through Adenosine A3 Receptor-Mediated Actions, Suppresses Amyloid Beta Precursor Protein Internalization and Amyloid Beta Generation. Journal of Alzheimer’s Disease 47 : 73–83. Chen X: Corresponding author

Hui L, Geiger NH, Bloor-Young D, Churchill GC, Geiger JD, Chen X. (2015) Release of calcium from endolysosomes increases calcium influx through N-type calcium channels: Evidence for acidic store-operated calcium entry in neurons. Cell Calcium 58(6):617-27

Chen X , Wagener JF, Ghribi O, Geiger JD. (2016) Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease. Front Aging Neurosci. 2016; 8:129. PMCID : PMC4896918. Chen X: Corresponding author

Chen X, Tian H, Ghribi O, and Geiger JD (2016) Caffeine blocks cholesterol-enriched diet induced AD-like pathology in rabbits. J Syst Integr Neurosci 2(1): 99-106. Chen X: Corresponding author

Li X, He S, Ye Y, Zhou X, Tan S, Jundt M.C., Lenz C, Lichter N, Hidebrand A, Wang Y, Li G, Huang C, and Wu M. Lyn delivers bacterial substance to lysosomes for eradication through TLR-2-initiated and autophagy-mediated phagocytosis. PLoS Pathogens 2016 Jan 6;12(1):e1005363. doi: 10.1371/journal.ppat.1005363. (Corresponding author

Chen HN, Yuan K, Xie N, Wang K, Huang Z, Chen Y, Dou Q, Wu M , Nice EC, Zhou ZG, Huang C. PDLIM1 stabilizes the E-cadherin/β-catenin complex to prevent epithelial-mesenchymal transition and metastatic potential of colorectal cancer cells. Cancer Res . 2016; 76(5):1122-34.  doi: 10.1158/0008-5472.CAN-15-1962.

Klionsky DJ, … Wu M , et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).   Autophagy 2016 Jan 2;12(1):1-222. No abstract available. PMID: 26799652

Zhu M, Zhao J, Kang H, Kong W, Zhao Y, Wu M , and Liang H. Modulation of Type III Secretion System in Pseudomonas aeruginosa: Involvement of the PA4857 Gene Product.   Front Microbiol 2016 Jan 28;7:7. doi: 10.3389/fmicb.2016.00007. eCollection 2016.

 Zhuang Y, Li Y, Li X, Xie Q, and Wu M . Atg7 knockdown augments Concanavalin A-induced acute hepatitis through an ROS-mediated p38/MAPK pathway. PLoS ONE 2016 Mar 3;11(3):e0149754. doi: 10.1371/journal.pone.0149754. (Corresponding author)

Zhao J, Yu X, Zhu M, Kang H, Ma J, Wu M , Gan J, Deng X, and Liang H. Structural and molecular mechanism of CdpR involved in quorum-sensing and bacterial virulence in Pseudomonas aeruginosa. PLOS Biol  2016 Apr 27;14(4):e1002449. doi: 10.1371/journal.pbio.1002449.

He S, Li X, Li R, Wang K, Fang L, Wang Y, and Wu M . Annexin A2 modulates ROS and thus impacts inflammatory response via IL-17 signaling in polymicrobial sepsis mice. PLoS Pathogens 2016; Jul 7;12(7):e1005743. doi: 10.1371/journal.ppat.1005743. (Corresponding author).

Li R, Tan S, Yu M, Li X, He S, Wei Y, and Wu M. Pseudomonas aeruginosa evades host immunity by Type I CRISPR-Cas mediated endogenous targeting. Cell Research 2016;26(12):1273-1287. doi: 10.1038/cr.2016.135. (with accompany research highlight paper and cover image, Corresponding author).  

Li R, Fang L, Pu Q, Lin P, Kannan S, Hoggarth A, Huang H, Li X, Li G, and Wu M . Lyn negatively regulates Pseudomonas aeruginosa-induced inflammatory responses through IL-6/STAT3/SHIP-1 signaling axis. Signaling Transduction and Therapeutic Targeting .  2016 ;1, Article number: 16032 (2016) doi:10.1038/sigtrans.2016.32 (With Editor’s summary and highlight, Nature-Springue Publishing) (Corresponding autho r).  

Wang X, Yang X, Li Y, Wang X, Zhang Y, Dai X, Niu B, Wu J, Yuan X, Xiong A, Liu Z, Zhong N, Wu M , and Li G. Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma. EBioMedicine  2016 Dec 21. pii: S2352-964(16)30589-8. doi: 10.1016/j.ebiom. (Elsevier, in press) (Co-corresponding author).

Tian H, Shi G, Wang Q, Li Y, Yang Q, Li C, Yang G, Wu M , Xie Q, Zhang S, Yang Y, Xiang R, Yu D, Wei Y, and Deng H. A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity. Signaling Transduction and Therapeutic Targeting.  2016;1, Article number: 16025; doi:10.1038/sigtrans.2016.25 (Nature-Springue Publishing).

Jondle CN, Sharma A, Simonson TJ, Larson B, Mishra BB, Sharma J . Macrophage Galactose-Type Lectin-1 Deficiency Is Associated with Increased Neutrophilia and Hyperinflammation in Gram-Negative Pneumonia. J Immunol . 2016 Apr 1;196(7):3088-96. doi: 10.4049/jimmunol.1501790.