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Current Openings

Graduate position available in Manu Lab

A PhD student position is available starting Spring, 2017 to study how gene regulatory networks process cytokine signals during mouse hematopoiesis. The student will work on a National Science Foundation funded project with the goals of 1) Identifying gene regulatory networks induced upon cytokine stimulation using gene expression time series data and 2) Developing predictive computational models to dissect the order and timing of regulatory events controlling cell-fate choice.

Our lab employs a variety of intertwined experimental and computational approaches to study cell-fate specification. See http://arts-sciences.und.edu/biology/faculty/manu.cfm for more information. The student will be joining an multidisciplinary team with expertise in developmental biology, computational biology, mathematical modeling, and high performance computing.

The student will be expected to perform computational analysis of RNA-seq data, formulate mathematical models of gene regulation, write software, and perform simulations. The opportunity to learn and perform experiments will also be available if the student is so inclined. The student will also be expected to collaborate with other members of the lab and interact with the larger integrative systems biology group comprised of faculty from the Departments of Biology, Mathematics, Physics, Chemistry, and Computer Science, and the Medical School.

Interested candidates should contact Dr. Manu by email or phone:

Manu, PhD
Assistant Professor of Biology
Starcher Hall 209
University of North Dakota
Office Phone: 701.777.4671
Email: manu.manu@und.edu

Postdoctoral position available in Manu Lab

There is a post doctoral position available in the Manu lab to study ene regulatory networks and gene regulation during hematopoiesis.

University of North Dakota, PostDoctoral Research Associate, Position #16542


The Biology Department at the University of North Dakota seeks a Postdoctoral Research Associate to study gene regulatory networks directing cell-fate decisions during hematopoiesis in an NSF-supported project. The appointment will be full-time and benefitted. 
 
The Postdoctoral Research Associate is a joint position between the laboratories of Dr. Manu (Department of Biology;  http://arts-sciences.und.edu/biology/faculty/manu.cfm ) and Dr. Loh (Department of Physics;  http://arts-sciences.und.edu/physics-astrophysics/loh/ ). We utilize tightly coupled experimental and computational approaches to uncover the gene regulatory logic underlying the differentiation of stem/multipotential progenitor cells into alternative lineages. Time resolved readouts of gene state, such as genome-wide gene expression, enhancer activity, and chromatin accessibility, are employed to constrain predictive mathematical models of gene regulation. Ongoing projects vary in scope from detailed cis-regulatory analyses of individual genes to broader studies of networks composed of dozens of genes. Our ultimate goal is to decode and model the regulatory logic of cell-fate decisions comprehensively, allowing the de novoprediction of gene expression dynamics in both normal development and reprogramming experiments.

The University of North Dakota has a vibrant and collaborative developmental biology and epigenetics community. The Manu lab is closely associated with an NIH funded Center for Biomedical Research Excellence focused on the epigenetics of development and disease ( http://www.med.und.edu/epigenetics/ ) hosted at the University of North Dakota. We also collaborate with several labs in the School of Medicine and Health Sciences (SMHS). The Department of Biology and SMHS feature modern molecular biology and functional genomics facilities. The Manu lab has a dedicated 96-CPU high performance computing cluster. 

Duties & Responsibilities
The Postdoctoral Research Associate will have the opportunity to work with a highly collaborative and multidisciplinary team developing novel approaches for inferring, modeling, and validating gene regulatory networks. We seek an independent experimental biologist with a strong interest in developmental biology and gene regulation and the ability to work collaboratively with other experimentalists and computational scientists. The postdoc will develop and implement projects, utilizing modern genome engineering and high-throughput sequencing approaches, to perturb gene networks for inferring their structure and expression dynamics. The postdoc will work closely with computational scientists to develop and validate mathematical models and will have the opportunity to learn computational techniques. The postdoc will disseminate the results of their work in the form of manuscripts and conference presentations. Successful candidates will be expected to mentor undergraduate and graduate students and interact with the larger developmental biology and epigenetics community at the University of North Dakota.

Minimum Qualifications

  • PhD in a developmental, molecular, cellular biology or related field. Candidates with PhDs in quantitative fields will also be considered provided they have significant wet lab experience in genetics and molecular biology

Preferred Qualifications

  • Experience in developmental genetics and molecular biology
  • Experience with genome engineering techniques and/or functional genomics
  • Experience with bioinformatics/computational biology
  • Strong record of scholarly publications

To Apply: Please submit cover letter, CV, and contact information for a minimum of three references.  Full consideration will be given to applications received by February 15, 2018.

If you have any questions, please contact Manu at manu.manu@und.edu

All applicants must apply here:  https://und.edu/finance-operations/human-resources-payroll/careers/secure/job-openings-external.cfm (Position #16542; JobID: 4067)


In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the US and to complete the required employment eligibility verification form upon hire. 

The University of North Dakota is an AA/EEO/Vets/Disabled Employer

 

Postdoctoral/Technician Position in Alexei Tulin Lab

Applications are invited for a postdoctoral position and a full-time technician position in the laboratory of Dr. Tulin.  Both positions are planned for at least three years, with a possibility of renewal. The successful applicants will conduct research on epigenetic regulation of normal development and carcinogenesis.  The primary research focus of Dr. Tulin’s lab is on fundamentals of chromatin regulation and RNA fate during normal development and in carcinogenesis, as well as on translating the findings of fundamental biology for clinical applications in oncology.  Projects in Dr. Tulin’s lab cover the molecular mechanisms of chromatin remodeling and regulation of gene expression and employ in vitro assays as well as human cells, mouse and Drosophila model organisms.

Applicants for the postdoctoral position should have a Ph.D. in molecular biology, molecular genetics, biochemistry, or a related field and no more than 3 years of postdoctoral research experience.  Experience in genetics, confocal microscopy, protein purification, live-cell imaging, and genomics / proteomics would be helpful.  Applicants for the technician position are required to have B.S. or M.S. in natural sciences or B.A. in biological anthropology. We will start reviewing the application immediately until the position is filled.  The top candidates will be invited for an interview and discussion of specific project.  All interviews will be conducted on-site and cannot be substituted by Skype or telephone discussion. 

To apply, please send or e-mail a letter of interest specifying your career goals, CV, and names of 3 references to:

 

Alexei V. Tulin, PhD
Professor, Epigenetics Group Leader
Columbia Hall Room 1733B
501 N Columbia Road
Office Phone: 701.777.9422
E-mail: Alexei.Tulin@med.und.edu

 

Postdoctoral positions available

Two postdoctoral positions are available: please see links below.

1) Post-doctoral research fellow in epigenetics/bioinformatics

2) Post-doctoral research fellow in bioinformatics and systems pharmacology