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- Center for Comparative Effectiveness Analytics
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- Center for Neurodegenerative Disorder Research
- Center of Biomedical Research Excellence in the Epigenomics of Development and Disease
- Center of Excellence for Host-Pathogen Interactions
- North Dakota IDeA Network of Biomedical Research Excellence (INBRE)
- Rural Health Reform Policy Research Center
- Seven Generations Center of Excellence in Native Behavioral Health
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- About Us
Colin K. Combs, PhD, Professor and Chair (PhD, University of Rochester): Mechanisms by which inflammatory activation of brain glial cells contributes to neurodegeneration. The process by which a specific type of glia, microglia, contribute to the pathophysiology of Alzheimer's disease.
David S. Bradley, PhD, Associate Professor (PhD, University of South Dakota School of Medicine): Influence of microbial agents and genetic polymorphism on altered host immune responses. Potential of infectious agents to act as "natural adjuvants" in individuals predisposed to autoimmunity. Potential role of mixed haplotype MHC class II molecules in the induction of polychondritis.
Catherine A. Brissette, PhD, Assistant Professor (PhD, University of Washington): Bacteria-host interactions with Borrelia burgdorferi. Regulation of virulence gene expression and bacterial interactions with the extracellular matrix.
Holly M. Brown-Borg, PhD, Chester Fritz Distinguished Professor (PhD, North Carolina State University): Understanding the relationship between cellular oxidation, hormones, mitochondrial activities and aging in a mammalian model of extended life span.
Edward C. Carlson, PhD, Professor (PhD, University of North Dakota): Transmission electron microscopic morphology of cellular components of the retinas of the eye and glomerulus of the kidney.
Patrick Carr, PhD, Associate Professor (PhD, University of Manitoba): The neurochemistry and synaptology of spinal cord and brainstem neurons, clinical anatomy, and educational issues regarding faculty development.
Lucia Carvelli, PhD, Assistant Professor (PhD, Mario Negri Institute for Pharmacological Research): Role of the dopaminergic system in addiction and pathological disorders such as ADHD, schizophrenia and Parkinson's disease.
Xuesong Chen, PhD, Assistant Professor (PhD, University of North Dakota): Understanding physiologically how endolysosomes contribute to calcium homeostasis in neurons, and pathologically how altered endolysosomal structure and function contributes to the pathogenesis of neurodegenerative diseases.
Danielle Jessen Condry, PhD, Assistant Professor (PhD, University of North Dakota): Teaching Responsibilities- Lecturer and lab instructor for courses: MBio 202 (Medical Microbiology), MBio 302 (General Microbiology), MBio 328 (Intro to Immunology), MBio 509 (Immunology), and MBio 494 (Peer Teaching).
Archana Dhasarathy, PhD, Assistant Professor (PhD, Texas A&M University): Epigenetic events leading to cancer metastasis.
Van A. Doze, PhD, Associate Professor (PhD, Stanford University): Function and modulation qf interneurons. Alterations in calecholaminergic transmission. Role of glial cells in neurodegeneration.
Jane R. Dunlevy, PhD, Associate Professor (PhD, University of Alabama at Birmingham): Cell biological changes that occur when cells are transformed from a normal cell type to a cancerous one by exposure to low levels of arsenite (As3+) or cadmium (Cd2+), SPARC expression in human bladder cells, and enolases in prostate cancer.
James D. Foster, PhD, Assistant Professor (PhD, the University of North Dakota): Regulation of the dopamine transporter (DAT) via phosphorylation and palmitoylation.
Jonathan D. Geiger, PhD, Chester Fritz Distinguished Professor (PhD, University of North Dakota): The ability of calcium in endosomes/lysosomes to influence capacitative influx of calcium and calcium-induced calcium release from ER and mitochondria. The role of endosome/lysosome dysfunction in animal models of Alzheimer's disease, HIV-1 associated dementia, and inclusion body myositis. The ability of caffeine to block adenosine receptors and protect against blood brain barrier dysfunction in animal models of Alzheimer's and Parkinson's disease. The role of brain energy metabolism in the pathogenesis of epilepsy and neurodegenerative diseases
Othman Ghribi, PhD, Associate Professor (PhD, Rene Descartes University): Role of diet and environmental factors in the pathogenesis of Alzheimer’s and Parkisnson’s disease. Neuroprotection against Alzheimer’s disease-like pathology in the brain. Role of Oxysterols and hypercholesterolemia in age-related macular degeneration.
Mikhail Golovko, PhD, Assistant Professor (PhD, Tver State University): Examining the lipid signaling pathway and inflammation response using steady-state kinetic modeling in vivo and mass spectrometric techniques.
Bryon Grove, PhD, Associate Professor (PhD, Clemson University): Role of proteins that anchor or target protein kinases and other intracellular proteins to specific cellular compartments, AKAPs (A-kinase anchoring proteins) in particular.
James R. Haselton, PhD, Assistant Professor (PhD, University of Miami): Central nervous system regulation of autonomic function.
L. Keith Henry, PhD, Associate Professor (PhD, University of Tennessee): The structural and molecular components of the serotonin and dopamine transporters and how they interact with drugs of abuse and antidepressants. Effect of antidepressant exposure on epigenetic regulation of the serotonergic system.
Malak Kotb, PhD, Professor
Saobo Lei, PhD, Associate Professor (PhD, University of Alberta): Modulation of synaptic transmission and plasticity in the hippocampus and entorhinal cortex. Roles of neuromodulators in epilepsy, anxiety and neurodegenerative diseases.
Mandy M. Meyer, PhD, Assistant Professor, Director of Deeded Body Program (PhD, University of North Dakota)
Barry I. Milavetz, PhD, Professor (PhD, University of Illinois): Role of epigenetics in the regulation of eukaryotic replication and transcription.
Bibhuti Mishra, PhD, Assistant Professor Neuroimmunology of parasitic diseases; C-Type lectin receptors in immunopathogenisis of brain parasitic infections; Helminth Immunoregulation- Characterization of immunosuppressive parasitic molecules, host receptors they interact with, modulation of signaling pathways and epigenetic mechanisms involved; Parasitic factors as therapeutic targets.
Eric J. Murphy, PhD, Associate Professor (PhD, The Ohio State University): How the brain maintain the unique lipid environment that is essential for normal brain function. The mechanisms underlying fatty acid uptake into the brain. N-3 Fatty acids in the human diet.
Sergei Y. Nechaev, PhD, Assistant Professor (PhD, Institute of Genetics and Selection of Industrial Microorganism): Investigating how one genome “encodes” multiple genetic programs to instruct formation of many distinct types of cells and how Pol II transcription coordinate genetic programs.
Matthew L. Nilles, PhD, Associate Professor (PhD, Washington State University): Regulation of toxin secretion in Yersinia pestis. Roles of the Y. pestis regulators LcrG and LcrV in the translocation of toxins into eukaryotic cells in response to bacteria-cell contact.
James Porter, PhD, Associate Professor (PhD, Creighton University): Characterization of molecular mechanisms for activating G protein-coupled receptor systems. Pharmacological classification of adrenergic receptors mediating the inhibition of GABAergic interneurons. Identification of signal transduction pathways causing the release of inflammatory factors initiated by sympathetic and peptidergic receptor activation.
Thad Rosenberger, PhD, Associate Professor (PhD, The Ohio State University): Identification of lipid-mediated signaling pathways that contribute to the progression of inflammatory events in the central nervous system. Identifying the specific roles phospholipases A2 and C play in the progression of disease. Distinguishing the role that ether phospholipid metabolism has in normal and injured brain.
Kenneth G. Ruit, PhD, Associate Professor (PhD, Loyola University of Chicago): Education with emphasis on medical curriculum innovation and program evaluation, assessment of student learning, and faculty development.
John B. Shabb, PhD, Associate Professor (PhD, West Virginia University): Proteomics, cellular signaling and cancer progression. Regulation of cellular processes by post-translational modifications including protein phosphorylation/dephosphorylation.
Jyotika Sharma, PhD, Assistant Professor (PhD, Kanpur University): Immune responses and host-pathogen interactions in pulmonary bacterial infections, particularly those leading to sepsis development.
Brij Singh, PhD, Professor (PhD, University of Bonn and Bhopal University): Characterization of calcium channel proteins, including regulation, membrane targeting, structure-function relationship, and mechanism of activation and inactivation.
Katherine A. Sukalski, PhD, Associate Professor (PhD, The University of North Dakota): Environmental factors in the progression of female basic science faculty to full professor and institutional leadership roles.
Chernet B. Tessema, MD, Assistant Professor (PhD, University Leipzig)
Roxanne A. Vaughan, PhD, Professor (PhD, Virginia Polytechnic Institute and State University): Structure-function properties of the dopamine transporter—a regulator of dopaminergic neurotransmission and site of action of cocaine and amphetamines.
John A. Watt, PhD, Associate Professor (PhD, Montana State University): Neuron/glial response(s) to brain injury, particularly in regards to the mechanisms of cellular communication involved in regenerative events.
Min Wu, PhD, Associate Professor (PhD, University of Leeds, United Kingdom): Mechanism of DNA damage and repair in lung oxidation and inflammation.
Marc Basson, MD, PhD, MBA, FACS, Professor, Surgery
Cindy Anderson, PhD, Adjunct Assistant Professor
Leslie M. Klevay, MD, Adjunct Professor
Joyce Ohm, PhD, Adjunct Professor
Matthew Picklo, PhD, Adjunct Associate Professor
Robert Sticca, MD, FACS, Adjunct Assistant Professor
Kate J. Claycombe, PhD, Human Nutrition Research Center
Huawei Zeng, PhD, Human Nutrition Research Center
Edward Carlson, PhD, Professor Emeritus
Roger Melvold, PhD, Professor Emeritus
David O. Lambeth, PhD, Professor Emeritus
Mary Bohlman, Administrative Assistant
Jennifer Hershey, Administrative Secretary
Julie Horn, Administrative Officer
Bonnie Kee, Administrative Assistant
Denelle Kees, Manager, Deeded Body Program
Michael Ullrich, Purchasing Assistant
Sarah Abrahamson, Confocal Technician
Steve Adkins, Laboratory Technician
Karthickeyan Chella Krishnan, Research Specialist
Angela Floden, Research Specialist
Atreyi Ghatak, Lab Tech
Svetlana Golovko, Research Specialist
Edie Green, Medical Technologist
Danping Guo, Research Technician
Julie Knutson, Research Assistant
Shawn Krueger, Lab Tech
Marge Larson, Laboratory Technician
Donna Laturnus, LM and EM Technician
Amanda Marquardt, Lab Tech
Wallace Muhonen, Research Specialist
Oscar Nnoli, Laboratory Technician
Danielle Perley, Lab Tech
Debbie Raasakka, Lab Tech
Shar Rakoczy, Research Specialist
Bryan Safratowich, Lab Tech
Adam Scheidegger, Research Specialist
Stacy Sailer, Laboratory Technician II
Kim Young, Medical Laboratory Tech. I (Electron Microscopic Facilities Technician)